Houtan Noushmehr

ORCID: 0000-0003-4051-8114 · 4 papers in corpus
other 2019
Cancer research ·doi:10.1158/0008-5472.can-17-3864

Genome-wide association studies have identified 40 ovarian cancer risk loci. However, the mechanisms underlying these associations remain elusive. In this study, we conducted a two-pronged approach to identify candidate causal SNPs and asse…

lab-animal 2018
PloS one ·doi:10.1371/journal.pone.0196913

Exosomes are endosome-derived membrane vesicles that contain proteins, lipids, and nucleic acids. The exosomal transcriptome mediates intercellular communication, and represents an understudied reservoir of novel biomarkers for human diseas…

lab-animal 2015
Human molecular genetics ·doi:10.1093/hmg/ddv101

Understanding the regulatory landscape of the human genome is a central question in complex trait genetics. Most single-nucleotide polymorphisms (SNPs) associated with cancer risk lie in non-protein-coding regions, implicating regulatory DN…

lab-animal 2014
Gynecologic Oncology ·doi:10.1016/j.ygyno.2014.06.016

BACKGROUND: Endometriosis is a common condition that is associated with an increased risk of developing ovarian carcinoma. Improved in vitro models of this disease are needed to better understand how endometriosis, a benign disease, can und…