Lixia Xu

No ORCID on file · 2 papers in corpus

other 2026

Identification and validation of circadian rhythm-related diagnostic biomarkers for endometriosis through integrating machine learning and single-cell analysis

European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2026.115521

BACKGROUND: Endometriosis (EMs) is a chronic inflammatory disease, and the lack of candidate molecular biomarkers remain a major clinical challenge. Circadian rhythm disruption plays a non-negligible role in EMs. However, the diagnostic pot…

review 2024

Molecular mechanisms and therapeutic significance of Tryptophan Metabolism and signaling in cancer

Molecular cancer ·doi:10.1186/s12943-024-02164-y

Tryptophan (Trp) metabolism involves three primary pathways: the kynurenine (Kyn) pathway (KP), the 5-hydroxytryptamine (serotonin, 5-HT) pathway, and the indole pathway. Under normal physiological conditions, Trp metabolism plays crucial r…