Bin Li

BACKGROUND: Smoking and alcohol consumption have been consistently associated with adverse female reproductive outcomes; however, whether these associations reflect causal effects or are mediated by specific circulating metabolites remains …

Mesonephric-like adenocarcinoma (MLA) is a rare gynecologic malignancy primarily arising in the uterine corpus and ovaries. It shares remarkable similarities in its histomorphology, immunophenotype, and molecular features with mesonephric a…

Ovarian cancer was the eighth most frequently diagnosed cancer among women in 2022. The global age-standardized incidence rate of ovarian cancer decreased from 7.22/100,000 to 6.71/100,000 from 1990 to 2021. However, incidence trends varied…

BACKGROUND: Endometriosis is currently considered a chronic disease for which long-term medical treatment is needed. The aim of this study was to evaluate the long-term efficacy and safety of dydrogesterone in Chinese women with endometrios…

Abstract Objective Investigating the therapeutic efficacy and safety of combined oral Chinese patent medicine with selective serotonin reuptake inhibitors (SSRIs) in special Homo sapiens populations with depressive disorders. Methods China …

Endometriosis (EMs) is a common gynecological disease accompanied by metabolic disturbances. However, the causality between metabolites and the risk of EMs remains unclear. We conducted a 2-sample Mendelian randomization (MR) analysis using…

The impaired endometrial receptivity is a major factor contributing to infertility in patients with endometriosis (EM), but the underlying mechanism remains unclear. Our study aimed to investigate the role of Kruppel-like factor 15 (KLF15) …

BACKGROUND: Ferroptosis, a recently discovered iron-dependent cell death, is linked to various diseases but its role in endometriosis is still not fully understood. METHODS: In this study, we integrated microarray data of endometriosis fro…

P: pelvic pain associated with EMs; I: acupuncture; C: non-penetrating needles; O: reduce the pain level.Condition being studied: The usage of acupuncture for pelvic pain caused by endometriosis is common, although studies have not been con…

This study aimed to investigate the metabolite profile and inflammatory state of follicular fluid (FF) in women with stage III-IV ovarian endometriosis (OE) who underwent in vitro fertilization (IVF). A cohort of 20 consecutive patients wit…

Methods: 450 infertile patients with severe endometriosis undergoing IVF/ICSI were randomized to: medroxyprogesterone acetate +hMG; dydrogesterone+hMG; and progesterone +hMG. Ovulation was induced with a gonadotropin-releasing hormone agoni…

Appendiceal or cecal endometriosis with intestinal metaplasia is uncommon and may mimic mucinous tumors of the appendix. A 50-year-old woman was found incidentally to have an ileocecal lesion. In the intraoperative histological examination,…

It is speculated that genetically modified food (GMF)/genetically modified organism (GMO) is responsible for infertility development. The risk linked with a wide use of GMFs/GMOs offers the basic elements for social criticism. However, to d…

Objective To clarify the clinical features,ultrasonic imaging changes and prognosis of neoplasias arised from endometriosis(EM). Methods A total of 23 women with ovarian neoplasia arising from EM were analyzed retrospectively,including clin…

OBJECTIVE: To study the effectiveness and safety of combined laparoscopy and gonadotropin-releasing hormone agonist (GnRH-a) in the treatment of endometriosis (EM). METHODS: From January to December 2010, 198 patients with EM undergoing tre…

AIM: To investigate whether intrinsic ureteral endometriosis could be managed by laser endoureterotomy. MATERIAL AND METHODS: We studied retrospectively 6 patients with intrinsic ureteral endometriosis who underwent laser endoureterotomy an…

目的探讨卵巢子宫内膜异位症（endometriosis，EM）瘤变的临床特点、超声图像特征及预后。方法回顾性分析23例卵巢EM瘤变的临床、超声及病理资料，随访其预后。结果卵巢EM恶变的高危因素有年龄〉45岁，特别是绝经后女性，异常阴道流血、腹痛性质改变，超声提示包块短期内迅速增大、囊肿直径〉8cm、囊壁见乳头或血流丰富。随访Ⅰ期患者16例均未见复发；Ⅲ～Ⅳ期患者3例均死亡。结论联合病史和经阴道彩色多普勒超声检查是早发现卵巢EM恶变的有效方法。

OBJECTIVE: To investigate the expression and signification of B-cell lymphoma/leukemia-2 (bcl-2), bax and ER proteins in epithelial cells in different depth of adenomyosis. METHODS: Expression and correlation of bcl-2, bax and ER proteins w…

BACKGROUND: Wide excision is considered the treatment of endometriosis. It is difficult to surgeon for reconstruction of a large full-thickness defect through the abdominal-wall. We introduce a method of mini-abdominoplasty combined with me…

OBJECTIVE: Although fibroids greatly affect reproductive health, the pathophysiology and epidemiology are not well known. Recently, we have reported the relationship between uterine leiomyoma and metabolic syndrome. Many studies have indica…

OBJECTIVE: To investigate the influence on ovarian reserve function in treatment of ovarian endometriotic cyst by laparoscopic cystectomy with various hemostasis management. METHODS: From September 2007 to August 2008, 61 patients with bila…

Objective To detect the effects of Survivin expression and angiogenesis on the etiology and progress in endometriosis and the correlation between them. Methods Seventeen samples of endometriomata,17 samples of eutopic endometrium of endomet…