Jean-Pierre A Kocher

No ORCID on file · 2 papers in corpus

diagnostic-accuracy 2020

Combining copy number, methylation markers, and mutations as a panel for endometrial cancer detection via intravaginal tampon collection

Gynecologic Oncology ·doi:10.1016/j.ygyno.2019.11.028

OBJECTIVE: We aimed to assess whether endometrial cancer (EC) can be detected in shed DNA collected with vaginal tampon by analyzing copy number, methylation markers, and mutations. METHODS: Tampons were collected prior to hysterectomy fro…

other 2015

TP53 mutations, tetraploidy and homologous recombination repair defects in early stage high-grade serous ovarian cancer

Nucleic acids research ·doi:10.1093/nar/gkv111

To determine early somatic changes in high-grade serous ovarian cancer (HGSOC), we performed whole genome sequencing on a rare collection of 16 low stage HGSOCs. The majority showed extensive structural alterations (one had an ultramutated …