Chiao-Wen Lin

No ORCID on file · 2 papers in corpus

lab-animal 2022

Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway

International journal of molecular sciences ·doi:10.3390/ijms23010484

Osteosarcoma is a highly common malignant bone tumor. Its highly metastatic properties are the leading cause of mortality for cancer. Niclosamide, a salicylanilide derivative, is an oral antihelminthic drug of known anticancer potential. Ho…

review 2019

TIMP-3 as a therapeutic target for cancer

Therapeutic advances in medical oncology ·doi:10.1177/1758835919864247

Tissue inhibitor of metalloproteinase-3 (TIMP-3), a secreted glycoprotein, plays an important role in carcinogenesis. It can bind to many proteinases to suppress their activity and thus protect the extracellular matrix from degradation. TIM…