Stefan P. Renner

Hintergrund: Die Risikostratifizierung der Endometriose ist ein Forschungsgebiet mit spärlichen Erkenntnissen. Endometriose und ein Uterus myomatosus werden als Risikofaktor für tubare Sterilität diskutiert. Ziel dieser großen deutschen End…

Question: Ulipristalacetate (UPA) has been previously demonstrated to inhibit the estradiol and progesterone induced proliferative response of normal endometrial cells in culture. We predicted that UPA would inhibit proliferation of endomet…

OBJECTIVE: To harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of human tissues relevant to endometriosis. DESIGN: An international collaboration involv…

OBJECTIVE: To harmonize the collection of nonsurgical clinical and epidemiologic data relevant to endometriosis research, allowing large-scale collaboration. DESIGN: An international collaboration involving 34 clinical/academic centers and…

OBJECTIVE: To harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, and storage of fluid biospecimens relevant to endometriosis. DESIGN: An international collaboration i…

An endometrioma (OMA) is the localization of endometriosis in ovary, and it most often develops as a cyst. The pathogenesis of OMA is still an open question and controversial; a cystic hemorrhagic corpus luteum may be a prerequisite, occurr…

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with epithelial ovaria…

OBJECTIVES: The aim of the current study was to evaluate the prevalence and the impact of sexual dysfunction, sexual distress and interpersonal relationships in patients with endometriosis. STUDY DESIGN: A questionnaire-based multicentre c…

Introduction: The German DRG system is annually adapted to the changing services provided. For the further development, the self-governing body and its DRG Institute (InEK) depend on participation of the users. Methods: For one of the DRG e…

Endometriose ist definiert als das Auftreten von endometrialen Zellverbänden außerhalb des Cavum uteri ([Tab. 1]). Mit 4–30 % aller Frauen im reproduktionsfähigen Alter stellt sie die häufigste gynäkologische Erkrankung dar. Nach Schätzunge…

OBJECTIVE: The aim of this study was to estimate the financial burden of in-patients costs for endometriosis treatment in Germany in 2006. METHODS: Data from a national in-patient database for women of reproductive age who were admitted fo…

Kernaussagen Zur Behandlung der Endometriose stehen verschiedene Maßnahmen zur Verfügung wie die endokrine, die symptomatische und die operative Therapie einzeln oder in Kombination. Die individuelle Situation der Patientin gilt es immer zu…

PURPOSE: The objectives of this study were to examine the age distribution among women suffering from endometriosis and to establish that endometriosis is not a disease that occurs only in premenopausal women. The null hypothesis was that t…

We identified differentially expressed genes comparing peritoneal endometriosis lesions (n = 18), eutopic endometrium (n = 17), and peritoneum (n = 22) from the same patients with complete menstrual cycles using microarrays (54 675 probe se…

PURPOSE: To construct pain maps in order to describe the distribution of pelvic pain in a group of endometriosis patients and endometriosis-free patients, to assess the feasibility of this method. METHODS: A total of 159 patients with pelv…

OBJECTIVE: An incidental finding of atypical endometrial hyperplasia (AEH) in women who have undergone laparoscopic supracervical hysterectomy (LASH) is a rare phenomenon, and it is unclear whether laparoscopic extirpation of the cervical s…

Objective: The etiology of endometriosis is still a research field in which few consistent data are available. Large case-control studies or even cohort studies are rare, and most of the published data are conflicting. The aim of the presen…

OBJECTIVE: To compare high-sensitivity C-reactive protein (hs-CRP) with CRP as a soluble serum marker for the diagnosis of women with endometriosis. DESIGN: Prospective nonrandomized controlled trial (Canadian Task Force classification II-…

BACKGROUND: The advantages and disadvantages of the various surgical techniques for hysterectomy are currently a topic of debate, with particular controversy over leaving the cervix in situ in the laparoscopic supracervical hysterectomy (LA…

Objective. Pain symptoms in endometriosis patients do not necessarily correlate with the extent of the disease, and there is little evidence regarding the recurrence risk. Aim of this study was to assess the risk factors for the recurrence …

OBJECTIVE: To investigate whether sexually transmitted viruses or prokaryotes, like human papilloma viruses (HPV), herpes viruses, and Chlamydia trachomatis, are associated with endometriosis lesions. DESIGN: Sixty-six endometriosis lesion…