Xi He

No ORCID on file · 3 papers in corpus
lab-animal 2026
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome
Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-026-06134-z

Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder and a major cause of female infertility. While epigenetic dysregulation, notably DNA methylation, has been recognized as a key driver of PCOS pathogenesis, the specific involv…

observational 2025
Dietary index for gut microbiota and its inverse association with female infertility: evidence from NHANES 2013-2018
Frontiers in nutrition ·doi:10.3389/fnut.2025.1564549

BACKGROUND: Infertility has become a global health concern, especially as the aging population continues to grow. Previous studies suggest that gut microbiota plays a crucial role in female reproductive health. This study aimed to investiga…

lab-animal 2023
Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome
Clinical epigenetics ·doi:10.1186/s13148-023-01487-9

Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder characterized by chronic low-grade inflammation. Previous studies have demonstrated that the gut microbiome can affect the host tissue cells' mRNA N6-methyladenosine (m…