Lei Wei

No ORCID on file · 4 papers in corpus
lab-animal 2026
Circ-MAP4K3 promotes papillary thyroid cancer progression by sponging miR-758-3p to enhance RRM2 expression
Clinical and experimental medicine ·doi:10.1007/s10238-026-02140-4

Papillary thyroid cancer (PTC) is an endocrine malignancy with a high incidence. PTC metastasizes more frequently in children and teenagers, although survival of these patients is usually considered excellent. Still, research on regulatory …

other 2026
Integrated analysis of isorhamnetin-associated targets in chronic pancreatitis and pancreatic cancer: immune-infiltration associations and antitumor effects in pancreatic cancer cells
Frontiers in immunology ·doi:10.3389/fimmu.2026.1902080

OBJECTIVE: Chronic pancreatitis (CP) creates an inflammatory pancreatic microenvironment and is an established risk factor for pancreatic cancer (PC). However, immune-inflammatory links between CP and PC remain unclear. Isorhamnetin (ISO), …

lab-animal 2024
Metastasis-associated lung adenocarcinoma transcript 1 overexpression in testis contributes to idiopathic non-obstructive azoospermia via repressing ETS variant transcription factor 5
Molecular biomedicine ·doi:10.1186/s43556-024-00235-6

Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), is a long non-coding RNA localized in the cell nucleus, known for its multifunctional roles, including potential involvement in spermatogenesis. This study investigates the me…

lab-animal 2011
MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.11-185132

Mechanical stress plays an essential role in tissue development and remodeling. In this study, we determined the role of microRNA in chondrocyte mechanotransduction. Using microarray, we identified miR-365 as a mechanoresponsive microRNA in…