Zilu Zhou

ORCID: 0000-0002-5554-8490 · 3 papers in corpus
lab-animal 2026
TREM2 deficiency attenuates endometriosis progression by inhibiting M2 polarization of SpMs and suppressing SIRPα to enhance phagocytosis†
Biology of reproduction ·doi:10.1093/biolre/ioag159

Endometriosis (EMS) is characterized by a disrupted peritoneal immune microenvironment where alternatively activated anti-inflammatory (M2) macrophage polarization and impaired phagocytosis promote lesion survival. Single-cell RNA-sequencin…

2025
Heme Inhibits the STING Pathway in Macrophages to Promote Endometriosis Development
·doi:10.1016/j.jri.2025.104695
lab-animal 2025
Hemin Inhibits the Activation of STING in Macrophages by Inducing HO-1, Promoting Endometriosis Development
·doi:10.1101/2025.10.25.683839

Abstract Introduction Endometriosis (EMS) is an estrogen-dependent inflammatory disorder characterized by immune dysregulation. This condition profoundly affects the quality of life and reproductive health of nearly 200 million women of rep…