Ptak A

ORCID: 0000-0003-3634-1918 · 5 papers in corpus
other 2026
Editorial: Advances on molecular mechanisms regulating reproduction - from gametogenesis to fertilization
Frontiers in molecular biosciences ·doi:10.3389/fmolb.2026.1850838
lab-animal 2026
Follicular fluid from women with polycystic ovary syndrome induces granulosa cells metabolic dysfunction that is exacerbated by obesity
Frontiers in endocrinology ·doi:10.3389/fendo.2026.1783780

BACKGROUND: Polycystic ovary syndrome (PCOS) is characterized by altered follicular development and metabolic dysfunction, frequently exacerbated by obesity. The follicular fluid (FF) microenvironment plays a critical role in supporting ooc…

other 2025
Energy imbalance in oPOI ovarian granulosa cells is linked to reduced glucose bioavailability and metabolism
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01426-8

BACKGROUND: Premature ovarian insufficiency (POI), affecting approximately 1% of women under 40, is associated with impaired fertility. Occult POI (oPOI), an initiating form, is more challenging to detect but still allows potential success …

review 2025
The Ovary as a Target Organ for New Generation Bisphenols Toxicity
Toxics ·doi:10.3390/toxics13030164

Bisphenols (BPs) are a group of organic compounds used extensively in plastics, coatings, and epoxy resins; they have been of concern recently due to their endocrine-disrupting effects. Among these, bisphenol A (BPA) is the most studied. Re…

lab-animal 2024
Myo-Inositol and D-Chiro-Inositol Reduce DHT-Stimulated Changes in the Steroidogenic Activity of Adult Granulosa Cell Tumors
International journal of molecular sciences ·doi:10.3390/ijms252010974

Considering the properties of myo-inositol (MI) and D-chiro-inositol (DCI), which are well known in polycystic ovary syndrome therapy, and the limitations of adult granulosa cell tumor (AGCT) treatment, especially for androgen-secreting tum…