Han Xu

ORCID: 0000-0002-1977-1046 · 3 papers in corpus
lab-animal 2026
Curcumin Inhibits Fibroblast Differentiation and Epithelial-Mesenchymal Transition to Alleviate Adenomyosis through TGF-β1/Smad3 Pathway
Chinese journal of integrative medicine ·doi:10.1007/s11655-025-4215-0

OBJECTIVE: To investigate the therapeutic effects and mechanisms of curcumin (Cur) in adenomyosis (AM). METHODS: A mouse uterine AM model was established by exposing ICR neonatal mice to tamoxifen (TAM). Female neonatal mice (day 1, n=24) …

rct 2025
Erzhi Tiangui formula increases the number of high-quality blastocysts in patients with advanced age by regulating the Nrf2/HO-1 signaling pathway: a randomized controlled study
Journal of ovarian research ·doi:10.1186/s13048-025-01940-8

BACKGROUND: Oxidative stress (OS) is a significant challenge in the in vitro embryo culture of patients of advanced age. The Erzhi Tiangui (EZTG) formula has been shown to alleviate OS-induced apoptosis in granulosa cells (GCs) of patients …

other 2024
Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-024-01263-1

BACKGROUND: Reduced endometrium thickness and receptivity are two important reasons for recurrent implantation failure (RIF). In order to elucidate differences between these two types of endometrial defects in terms of molecular signatures,…