Chang L

Deep infiltrating endometriosis (DIE) and focal adenomyosis of the outer myometrium (FAOM) are closely related chronic inflammatory conditions that often coexist. The systemic immune-inflammation index (SII), systemic inflammation response …

OBJECTIVES: To evaluate the feasibility of quantitative susceptibility mapping (QSM) and R2* mapping in assessing iron deposition in endometriotic ovarian cysts (EMO) and their potential implications for ovarian reserve. MATERIALS AND METH…

OBJECTIVE: To quantitatively map and visualize global research trends, key contributors, and thematic evolution in fertility-preserving treatment for endometrial cancer from 2005 to 2024. METHODS: Research publications on fertility-preserv…

OBJECTIVES: This study aims to evaluate the diagnostic value of amide proton transfer-weighted (APTw) imaging in distinguishing cystic or predominantly cystic ovarian lesions. MATERIALS AND METHODS: 49 patients underwent APTw imaging at 3T…

BACKGROUND: Endometriosis is a common disease among women of childbearing age. However, the molecular mechanism behind it is still unknown. Therefore, new biomarkers and therapeutic targets are needed to improve the diagnosis and treatment …

Infertility poses considerable challenges to both the endocrine system and psychological well-being of affected women. In particular, those undergoing Assisted Reproductive Technology (ART) confront not only physiological demands but also s…

Endometriosis (EMS) is an estrogen-dependent disorder that affects about 10% of reproductive-age women. EMS affects female neuroendocrine and reproductive functions, greatly compromising female reproductive health and quality of life. Howev…

We compared ovarian cancer incidence between women with and without an index irritable bowel syndrome (IBS) diagnosis using administrative claims data. Risk of ovarian cancer was higher at 3 (hazard ratio [HR] = 1.71, 95% CI: 1.08-2.70, p =…

BACKGROUND: Intravenous leiomyomatosis (IVL) is a rare benign smooth muscle tumor, for which the ultrasound features and diagnostic value have rarely been reported due to its infrequent presentation. This study aimed to analyze ultrasonogra…

BACKGROUND: Hereditary primary hyperparathyroidism (PHPT) accounts for 5-10% of all PHPT cases, necessitating genetic testing for diagnosis and management. Among these, hyperparathyroidism-jaw tumor syndrome (HPT-JT) is an autosomal dominan…

BACKGROUND: The effects of female chromosomal polymorphisms (FCPs) on various aspects of reproductive health have been investigated, yet the findings are frequently inconsistent. This study aims to clarify the role of FCPs on the outcomes o…

Abstract Background: Endometriosis is a common disease among women of childbearing age. However, the molecular mechanism behind it is still unknown. Therefore, new biomarkers and therapeutic targets are needed to improve the diagnosis and …

Study questionWhat are the roles of maternal 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C combination polymorphisms on the embryological and clinical outcomes of IVF/ICSI?Summary answerOur study reveals for the first time t…

OBJECTIVE: Endometriosis, which is a common disease affecting approximately 10% of women of reproductive age, usually causes dysmenorrhea and infertility, thus seriously harming the patients' physical and mental health. However, there is a …

BACKGROUND & AIMS: Many studies have assessed risk factors of irritable bowel syndrome (IBS) and other abdominal pain-related disorders of gut-brain interaction (AP-DGBI); however, the role of these factors is unclear due to heterogeneous s…

The current biomarkers available in the clinic are not enough for early diagnosis or for monitoring disease progression of ovarian cancer. Liquid biopsy is a minimally invasive test and has the advantage of early diagnosis and real-time mon…

Obesity-related non-alcoholic fatty liver disease (NAFLD) is connected with mitochondrial stress and hepatocyte apoptosis. Parkin-related mitophagy sustains mitochondrial homeostasis and hepatocyte viability. However, the contribution and r…

OBJECTIVES: Adverse events (AEs) of ischemic colitis (IC) and complications of constipation (CoC) associated with alosetron are rare and have been adjudicated during the first 5.5 years of the risk management program (RMP); however, changes…

BACKGROUND: An increase in gastrointestinal (GI) symptoms, including bowel discomfort, abdominal pain/discomfort, bloating, and alterations in bowel patterns, has been reported during premenses and menses menstrual cycle phases and the peri…

BACKGROUND: Diagnostic laparoscopy is minimally invasive surgery for the diagnosis of intraabdominal diseases. The aim of this review is a critical examination of the available literature on the role of laparoscopy for chronic intraabdomina…