Shidou Zhao

No ORCID on file · 5 papers in corpus
lab-animal 2025
Nature aging ·doi:10.1038/s43587-025-00927-w

Reproductive longevity is essential for female fertility and healthy aging; however, the role of stress response, especially stress granule accumulation, in ovarian aging remains elusive and interventions are lacking. Here, we identified de…

lab-animal 2021
Molecular therapy. Nucleic acids ·doi:10.1016/j.omtn.2020.10.041

Dysfunction of granulosa cells (GCs) leading to follicle atresia has been extensively studied as a major cause of premature ovarian insufficiency (POI), but the regulatory role of long non-coding RNAs (lncRNAs) in this process is still poor…

lab-animal 2021
Clinical and translational medicine ·doi:10.1002/ctm2.448

Immune dysregulation has long been proposed as a component of premature ovarian insufficiency (POI), but the underlying mediators and mechanisms remain largely unknown. Here we showed that patients with POI had augmented T helper 1 (TH 1) r…

observational 2020
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13292

PROBLEM: Premature ovarian insufficiency (POI) imposes great challenge on female reproduction. Whether immune disturbance in ovarian environment was implicated in POI remains unclear. We aimed to characterize the cytokine profile in follicu…

other 2020
Nucleic acids research ·doi:10.1093/nar/gkaa127

The genetic etiology of premature ovarian insufficiency (POI) has been well established to date, however, the role of long noncoding RNAs (lncRNAs) in POI is largely unknown. In this study, we identified a down-expressed lncRNA HCP5 in gran…