Helena Malvezzi

ORCID: 0000-0002-5504-6116 · 27 papers in corpus · active 2011-2025

Study types

  • article 14
  • review 7
  • other 4
  • dataset 1
  • erratum 1

Condition tags

  • endometriosis 26
  • mesh:D004715 18
  • infertility 7
  • chronic_pelvic_pain 3
  • mesh:D017699 2
  • die_deep_infiltrating 2
  • endometrioma 1
other 2025
Einstein (Sao Paulo, Brazil) ·doi:10.31744/einstein_journal/2025AO1345

BACKGROUND: This study reveals elevated levels of MMP-1, MMP-2, and MMP-3 in endometriotic lesions, potentially reflecting a senescenceassociated secretory phenotype. No corresponding increase was observed in peritoneal fluid, possibly due …

other 2025
Microbial pathogenesis ·doi:10.1016/j.micpath.2024.107244

Endometriosis is a chronic gynecological disease that affects 10 % of reproductive-aged women and characterized by the presence of endometrial tissue outside the uterus. The disease is linked to a pro-inflammatory environment in the periton…

article 2023
International journal of molecular sciences ·doi:10.3390/ijms24020914

Endometriosis affects a significant proportion of women worldwide; however, no definitive cure for this disease has been discovered to date. Oxidative stress promotes endometriotic lesion maintenance in the peritoneal cavity in women. Furth…

article 2023
·doi:10.61622/0100-7254514202306

RESUMO Objetivo Averiguar o conhecimento das adolescentes sobre endometriose, que é uma doença estrogênio-dependente, podendo ser progressiva, e que se caracteriza pela presença do tecido endometrial fora do útero. Estima-se que a endometri…

article 2022
International journal of molecular sciences ·doi:10.3390/ijms23052476

Endometriosis causes immunological and cellular alterations. Endometriosis lesions have lower levels of lamin b1 than the endometrium. Moreover, high levels of pro-inflammatory markers are observed in the peritoneal fluid, follicular fluid,…

review 2022
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia ·doi:10.1055/s-0042-1742406

Abstract Introduction Endometriosis is an inflammatory disease that affects women of reproductive age, causing pain and the possibility of infertility. Endometriosis was associated to low life quality and research shows the impact of endome…

review 2022
·doi:10.6084/m9.figshare.20178446

Abstract Introduction Endometriosis is an inflammatory disease that affects women of reproductive age, causing pain and the possibility of infertility. Endometriosis was associated to low life quality and research shows the impact of endome…

article 2022
Scientific reports ·doi:10.1038/s41598-022-21431-w

Abstract Endometriosis is a prevalent gynecological condition with deleterious effects on women’s quality of life in terms of physical, emotional, and social compromise. It is an inflammatory disease characterized by the presence of endomet…

other 2022
Frontiers in molecular biosciences ·doi:10.3389/fmolb.2022.854991

Endometriosis is a highly prevalent gynecological disease characterized by lesions in different sites. Regulation of specific estrogen pathways may favor the formation of distinct microenvironments and the progression of endometriosis. Howe…

dataset 2021
·doi:10.6084/m9.figshare.14317095

Abstract Objective The present study is a systematic review of the literature to assess whether the presence of endometriosis determines or contributes to adverse obstetric outcomes. Data Sources The present work was carried out at the Hosp…

review 2020
Journal of translational medicine ·doi:10.1186/s12967-020-02471-0

Endometriosis is a chronic inflammatory hormone-dependent condition associated with pelvic pain and infertility, characterized by the growth of ectopic endometrium outside the uterus. Given its still unknown etiology, treatments usually aim…

article 2020
·doi:10.1016/j.fertnstert.2020.08.243
review 2020
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia ·doi:10.1055/s-0040-1708885

Abstract Objective The present study is a systematic review of the literature to assess whether the presence of endometriosis determines or contributes to adverse obstetric outcomes. Data Sources The present work was carried out at the Hosp…

article 2020
Molecules (Basel, Switzerland) ·doi:10.3390/molecules25061325

There is increasing interest in the potential of natural compounds to treat diseases, such as endometriosis, a gynecological disorder that affects 10–15% of women of reproductive age, and it is related to severe pelvic pain and infertility.…

review 2019
Reproduction (Cambridge, England) ·doi:10.1530/rep-18-0618

The objective is to study the significance of altered interleukin levels in endometriosis-related infertility or pelvic pain. The present systematic review and meta-analysis includes a discussion on the roles of interleukin in the physiopat…

article 2019
Medicina (Kaunas, Lithuania) ·doi:10.3390/medicina55090520

Background and Objectives: The presence of endometrial-like tissue outside the uterine cavity is a key feature of endometriosis. Although endometriotic lesions appear to be histologically quite similar to the eutopic endometrium, detailed s…

article 2018
other 2018
Archives of gynecology and obstetrics ·doi:10.1007/s00404-018-4691-y

PROPOSE: Endometriosis is a benign disease characterized by implantation and the growth of endometrial tissue outside the uterine cavity and it shares similarities with cancer. Lamin B1, p16 and p21 play a role on cell cycle regulation, dev…

article 2018
Cell and tissue research ·doi:10.1007/s00441-018-2805-2
review 2018
Journal of molecular endocrinology ·doi:10.1530/jme-17-0297

Endometriosis is an incurable hormone-dependent inflammatory disease that causes chronic pelvic pain and infertility characterized by implantation and growth of endometrial tissue outside the uterine cavity. Symptoms have a major impact on …

erratum 2017
Journal of reproductive immunology ·doi:10.1016/j.jri.2017.05.004
review 2017
Journal of reproductive immunology ·doi:10.1016/j.jri.2017.04.003
article 2013
Human Reproduction ·doi:10.1093/humrep/det378

This study was supported by the National Council for Scientific and Technological Development (CNPq), Brazil. The authors declare no conflicts of interest.

article 2013
Minerva ginecologica

Increasing evidence suggests that female infertility is associated with endometriosis. Indeed, 40% of women with this disease are infertile. However, a causal relationship has not yet been established, and the possible pathophysiology of in…

article 2013