Chen J

The presence of endometrial tissue outside the uterus is a defining characteristic of endometriosis, a chronic systemic illness that affects women of childbearing age. Despite its enigmatic nature, laparoscopy remains the gold standard for …

BACKGROUND: Deep infiltrating endometriosis is a subtype of endometriosis. A case of retroperitoneal endometriosis surrounding the ureter and forming a pelvic mass is relatively rare. CASE PRESENTATION: A 26-year-old woman was admitted to …

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic condition in reproductive-aged women, linked to infertility and long-term cardiometabolic risk. Early identification remains challenging because current diagnosis …

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. It is characterized by symptoms such as hyperandrogenemia, oligo or anovulation and polycystic ovarian, significantly impacting…

Liver fibrosis is induced by persistent stimulation of various factors, resulting from complex multicellular interactions and multifactorial networks. Without intervention, it can progress to cirrhosis and even liver cancer. Current underst…

BACKGROUND: For poor ovarian response patients, obtaining higher number of transferable and high-quality embryos is crucial and progestin-primed ovarian stimulation protocol is becoming widespread and constantly improving in this population…

OBJECTIVE: The objective of this study was to assess the efficacy of focused ultrasound ablation surgery (FUAS) in treating patients with adenomyosis and coexisting pelvic adhesions. MATERIALS AND METHODS: A total of 396 patients diagnosed…

BACKGROUND: Melatonin is mainly secreted by the pineal gland during darkness and regulates biological rhythms through its receptors in the suprachiasmatic nucleus of the hypothalamus. In addition, it also plays a role in the reproductive sy…

Emerging but inconsistent evidence suggests that glyphosate (GLY)-based herbicides (GBHs) are more toxic than the active ingredient, GLY alone. Polyoxyethylene tallow amines (POEAs) are surfactants most widely used in GBH formulations, maki…

Objective: To synthesize the multifactorial determinants of fertility distress among reproductive-aged women with gynecological cancers, elucidating complex interactions among biological, psychological, and sociocultural dimensions. Methods…

OBJECTIVE: Magnetic resonance elastography (MRE), a novel imaging technique that allows in vivo measurement of tissue mechanical properties, was used to test the prediction that the stiffness of the uterus may be increased due to fibrotic c…

Ovarian cancer (OC) is a deadly disease and lacks a precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin-1 (FLOT1) in OC tissue. To improve diagnostic sensitivity and accuracy, we evaluated the…

BACKGROUND: Gasless transvaginal natural orifice transluminal endoscopic surgery (G-vNOTES) can avoid complications related to pneumoperitoneum, but there is limited research on G-vNOTES. Here, we aimed to compare the hemodynamic profiles a…

Ectopic pancreas (EP) is most commonly located in the upper gastrointestinal tract, particularly in the stomach. Malignant transformation of EP is exceptionally rare, and due to its very low incidence, the response to drug therapy and overa…

Ovarian cancer remains a formidable global health burden, characterized by frequent late-stage diagnosis and elevated mortality rates attributable to its elusive pathogenesis and the critical lack of reliable early-detection biomarkers. Eme…

In this single-center, double-blinded, randomized controlled trial, we investigated whether human umbilical cord-derived mesenchymal stromal cells loaded collagen scaffolds (hUC-MSC/CS) could improve the cumulative live-birth rate (cLBR) in…

Background and Objectives: Hysterectomy is a common non-obstetric procedure. Minimally invasive techniques, such as laparoscopy and robot-assisted surgery, have replaced open surgery for benign gynecologic conditions. Robotic surgery offers…

Background: Acute pancreatitis (AP) is characterized by the abnormal activation of pancreatic enzymes due to various causes, leading to local pancreatic inflammation. This can trigger systemic inflammatory response syndrome and multi-organ …

Inflammatory bowel disease (IBD) is an inflammatory disease of the intestine whose primary pathological presentation is the destruction of the intestinal epithelium. The intestinal epithelium, located between the lumen and lamina propria, t…

OBJECTIVE: To determine whether follicle size at midcycle transvaginal sonography imaging before luteal progesterone supplementation predicts modified natural cycle single frozen embryo transfer (mNC-SFET) outcomes. DESIGN: Retrospective c…

Background: Tuberculosis is a communicable disease that is a major cause of ill health and one of the leading causes of death worldwide. Latent tuberculosis infection (LTBI) widely exists in people all over the world, especially in patients…

This study attempted to evaluate the incidence of incidentalomas based on computed tomography (CT) in colorectal cancer (CRC) patients. CRC patients who obtained plan or enhanced CT for the whole abdominal and pelvis were included at the Fi…

Defective endometrial receptivity represents an important factor in recurrent implantation failure (RIF), though its precise regulatory mechanisms remain unclear. While nicotinamide N-methyltransferase (NNMT) is abundantly expressed in huma…

Endometriosis (EM) is a chronic, estrogen-dependent disease characterized by the ectopic presence of endometrial-like tissue. Despite extensive research, its molecular pathogenesis remains unclear. In this study, we conducted an integrated …

PURPOSE: To compare the clinical outcomes of extremely poor responders with one or two oocytes who receive in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). METHODS: A retrospective study was carried out on 2572 pat…