Filiberto Maria Severi

BACKGROUND: Ovarian remnant syndrome (ORS) is a rare condition defined by the presence of residual tissue of ovarian origin, histologically confirmed in a woman with a previous salpingo-oophorectomy, usually as a result of difficult surgery…

OBJECTIVE: To evaluate pregnancy, delivery and neonatal outcome in singleton primiparous versus multiparous women with/without endometriosis. METHODS: Multicentric, observational and cohort study on a group of Caucasian pregnant women (n =…

OBJECTIVE: To evaluate the clinical efficacy and patient satisfaction of danazol delivered vaginally as treatment for young women with menorrhagia. DESIGN: Prospective study. SETTING: University of Siena, Siena, Italy. PATIENT(S): Women …

In the recent years, the research involved to clarify the mechanisms of endometriosis development opened new innovative treatments. In fact, not only new drugs have been studied but also new routes of administration for hormones have been i…

A danazol-loaded intrauterine device (IUD) containing 300-400 mg of danazol was inserted for 6 months in a group of women (n = 18) (median age 36.6 years; age range: 30 to 46 years) with a histologic diagnosis of endometriosis, referred for…

LHRH tests were performed in two children with Bartter's syndrome before and during treatment with prostaglandin synthesis inhibitors. Before treatment, in patient 1 both basal and peak FSH and LH levels were elevated; in patient 2 basal an…