In recent decades, we have observed a remarkable increase in the rate of caesarean section (CS) in both developed and developing countries, especially in China. According to the World Health Organization (WHO) systematic review, if the incr…
BACKGROUND: Epidemiological studies have sought to establish a relationship between a woman's current body mass index and endometriosis, but with varying results. This meta-analysis was to summarize the current epidemiological evidence. ME…
OBJECTIVE(S): Adenomyosis and endometriosis are two different diseases, although they have similar pathogenesis and characteristic. The serum differential expressed proteins in adenomyosis and endometriosis may result from the different pat…
BACKGROUND: Both endometriosis and adenomyosis are common benign gynecological diseases. This study aimed to find the novel noninvasive, biochemical diagnostic markers for detection of endometriosis and adenomyosis, and evaluate the correla…
Objective:To detect specific serum biomarkers of adenomyosis by surface-enhanced laser desorption/ ionization time-of-flight mass spectrometry(SELDI-TOF-MS) technology.Methods:Serum samples from women with adenomyosis were compared with nor…
OBJECTIVE: To employ the classical Wnt/β-catenin signaling pathway interference to explore the effects on the functional changes of eutopic endometrium stromal cells and the differences between endometriosis in a murine model. METHODS: Two…
OBJECTIVE: To establish the model of cultivating and identifying fibroblast from human endometriosis (HEFC) in vitro. METHODS: The tissues of human endometriotic cysts of ovary were digested by collagenases I, II and IV The resulting cells…
OBJECTIVE: To establish the methods of isolating and culturing human ovarian endometriosis-derived microvascular endothelial cells (OEMEC). METHODS: The tissues of human endometriotic cyst of ovary were finely minced with scissors, then di…
OBJECTIVE: To study the expression of nociceptin in adenomyosis tissue and understand its relationship with the severity of dysmenorrhea. METHODS: The myometrial specimens were collected from 55 patients undergoing hysterectomy at our hosp…