Haiou Liu

ORCID: 0000-0003-0200-8981 · 15 papers in corpus
lab-animal 2025
Experimental cell research ·doi:10.1016/j.yexcr.2025.114654

PURPOSE: The study was designed to investigate whether estrogen regulates cell migration through cell polarity signaling and contributes to adenomyosis development. METHODS: In vitro study, Ishikawa cells received different treatments, Wes…

lab-animal 2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.787876

BACKGROUND: Low-grade chronic inflammation may contribute to the pathogenesis of polycystic ovary syndrome (PCOS). Interleukin-15 (IL-15) is a proinflammatory cytokine involved in the development of chronic inflammation leading to obesity-a…

other 2021
Biology of reproduction ·doi:10.1093/biolre/ioab017

Differentiation of endometrial stromal cells (ESCs) into secretory decidualized cells (dESCs) is essential for embryo implantation. Adenomyosis is a common benign gynecological disease that causes infertility. However, whether adenomyosis a…

lab-animal 2021
Human Reproduction ·doi:10.1093/humrep/deab234

STUDY QUESTION: Does Scribble (SCRIB) contribute to aberrant decidualization of endometrial stromal cells (ESC) in adenomyosis? SUMMARY ANSWER: SCRIB knockdown impairs decidualization of ESC by decreasing Fork-head box O1A (FOXO1) expressi…

lab-animal 2020
Experimental and therapeutic medicine ·doi:10.3892/etm.2020.8580

The aim of the present study was to evaluate the effects of the selective cyclooxygenase (COX)-2 inhibitor celecoxib on the development of uterine adenomyosis in mice. ICR neonatal mice were first exposed to tamoxifen to establish a mouse m…

observational 2019
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.13952

AIM: Previous studies have revealed that loss of cell apical-basal polarity contributed to the early stages of tumorigenesis. Adenomyosis involves a down-growth and aberrant implantation of the endometrial basalis into the myometrium. This …

lab-animal 2019
Biology of reproduction ·doi:10.1093/biolre/ioz194

Despite its prevalence and the severity of symptoms, little is known about the pathogenesis and etiology of adenomyosis. In previous studies, the protein expression level of the polarity protein Scribble in the eutopic endometrium of patien…

other 2019
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118812737

Adenomyosis is a common gynecological disease, characterized by the existence of endometrium in the myometrium. The pathogenesis of adenomyosis is not fully understood. P21-activated kinase 1 (PAK1) is an effector of small Rho GTPases inclu…

other 2018
·doi:10.25384/sage.c.4307960.v1

Adenomyosis is a common gynecological disease, characterized by the existence of endometrium in the myometrium. The pathogenesis of adenomyosis is not fully understood. P21-activated kinase 1 (PAK1) is an effector of small Rho GTPases inclu…

other 2018
·doi:10.25384/sage.c.4307960

Adenomyosis is a common gynecological disease, characterized by the existence of endometrium in the myometrium. The pathogenesis of adenomyosis is not fully understood. P21-activated kinase 1 (PAK1) is an effector of small Rho GTPases inclu…

other 2018
·doi:10.25384/sage.7364423

Supplemental Material, Figure_S1 for P21-Activated Kinase 1 Overactivates in Eutopic Endometrium of Adenomyosis by Weiwen Zuo, Xiaoyi Wu, Haiou Liu, and Congjian Xu in Reproductive Sciences

other 2018
·doi:10.25384/sage.7364423.v1

Supplemental Material, Figure_S1 for P21-Activated Kinase 1 Overactivates in Eutopic Endometrium of Adenomyosis by Weiwen Zuo, Xiaoyi Wu, Haiou Liu, and Congjian Xu in Reproductive Sciences

observational 2017
PloS one ·doi:10.1371/journal.pone.0177520

Chronic inflammation is a well-known epidemiologic factor of ovarian clear cell carcinomas (OCCC), but has an uncertain role in prognosis. We developed a systemic inflammation score (SIS) based on preoperative serum albumin and neutrophil-t…

observational 2016
Oncotarget ·doi:10.18632/oncotarget.13967

BACKGROUND: Despite enormous efforts to dissect the role of endometriosis in ovarian cancer development, the difference in prognosis between ovarian cancer patients with or without endometriosis remains elusive. The purpose of this study is…

lab-animal 2014
PloS one ·doi:10.1371/journal.pone.0087978

Generally, most of ovarian cancer cannot be detected until large scale and remote metastasis occurs, which is the major cause of high mortality in ovarian cancer. Therefore, it is urgent to discover metastasis-related biomarkers for the det…