According to the most recent World Health Organization report in 2022, approximately 16% of people were classified as obese. Obesity is an inflammatory-mediated condition manifested by accelerated lipogenesis and excessive fat accumulation …
Endometriosis (END) is a gynecological disease marked by the presence of endometrial-like tissue outside the uterus, inducing estrogen-driven inflammation that manifests through chronic pelvic pain, dysmenorrhea, and infertility, which impa…
BACKGROUND: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor historically recognized for its role in the regulation of toxicity mediated by environmental chemicals. Recent research points to AhR's critical part…
INTRODUCTION: Endometriosis is a painful disease that affects around 5% of women of reproductive age. In endometriosis, ectopic endometrial cells or seeded endometrial debris grow in abnormal locations including the peritoneal cavity. Commo…
The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), an environmental contaminant, is a potent ligand for aryl hydrocarbon receptor (AhR). In the current study, we made an exciting observation that naive C57BL/6 mice that were exposed i…
Abstract Ectopic growth of normal cells or debris originating from endometrium, the inner layer of female reproductive tube leads to endometriosis. The main symptoms are dyspareunia, dysmenorrhea, and sometimes chronic pelvic pain. Unfortun…