Chenglei Gu
ORCID: 0000-0002-9009-464X
· 10 papers in corpus
lab-animal
2026
OBJECTIVES: The expression of GSDMD and GSDME in ovarian cancerous tissues, adjacent tissues, and cancer cell lines remain poorly characterized. The contribution of pyroptosis to the synergistic therapeutic effects of PI3K-AKT-mTOR inhibito…
observational
2025
Performing robotic hysterectomy (RH) on large uteri is a significant challenge. This study aims to investigate the impact of various risk factors on surgical outcomes and to identify the most effective surgical approach for performing RH on…
other
2021
PURPOSE: The etiology and pathophysiology of endometriosis remain unclear. Current research indicates long noncoding RNA (lncRNA) may play an important role in the pathogenesis and development of endometriosis. However, the molecular mechan…
other
2020
Endometriosis, as a prevalent gynecological disease, is characterized by the presence of endometrial-like tissue outside the uterus, causing infertility and considerable pain and affecting the quality of life of women. The pathogenic mechan…
lab-animal
2018
BACKGROUND/AIMS: Mitochondrial homeostasis is implicated in the development and progression of endometriosis through poorly defined mechanisms. Mst1 is the major growth suppressor related to cancer migration, apoptosis and proliferation. Ho…
other
2018
BACKGROUND: The etiology and pathophysiology of endometriosis remain unclear. Accumulating evidence suggests that aberrant microRNA (miRNA) and transcription factor (TF) expression may be involved in the pathogenesis and development of endo…
other
2017
The etiology and pathophysiology of endometriosis remain unclear. The aim of the current study was to identify a candidate pathogenic gene, as well as potential biomarkers of endometriosis using messenger RNA (mRNA) sequencing (mRNA-seq). T…
meta-analysis
2016
The PvuII (C > T), XbaI (A > G) and (TA)n polymorphisms of ESR1 gene are potentially associated with susceptibility to endometriosis. A meta-analysis was conducted to evaluate comprehensively the associations between endometriosis and ESR1 …
review
2016
Endometriosis is a common gynecological disease with high prevalence, while its etiology and pathophysiology have remained to be fully elucidated. Previous evidence suggested that this disorder may be in part or completely of somatic origin…
2016
Objective To evaluate the effectiveness and safety of postmenopausal ovarian endometrial cyst. Methods From Jun. 2010 to Jun. 2015, there were 31 patients of postmenopausal ovarian endometriosis treated with laparoscopic surgery in o…