Michel Canis

INTRODUCTION: Numerous studies have shown that the diagnostic performance and reproducibility of visual recognition of endometriosis during laparoscopy are poor. The use of artificial intelligence (AI) seems relevant for exhaustive lesion r…

OBJECTIVE: To develop best practice guidelines under the auspices of the CNGOF (National college of French Gynaecologist Obstetrician) and Convergences PP (Convergences in Pelviperineal Pain) for the management of endometriosis-associated p…

OBJECTIVES: Endometriosis is an estrogen-dependent disease, and hormonal treatment is the most common treatment. Both deep infiltrating endometriosis (DIE) and ovarian endometrioma (OV) are characterized by dense surrounding fibrotic tissue…

Whether endometriosis is a progressive disease remains debated. Central to this debate is understanding the natural history of endometriotic lesions, which are essentially wounds undergoing repeated tissue injury and repair. Viewing the dis…

BACKGROUND: Rectal endometriosis is among the most symptomatic forms of the disease. When hormonal therapy fails, surgery is often required. High-intensity focused ultrasound (HIFU) is widely used in gynecology for the treatment of myomas a…

A growing body of literature has revealed that patients with endometriosis are at an increased risk for epithelial ovarian cancer (EOC) and cardiovascular disease (CVD). Endometriosis is a heterogeneous disease in terms of its clinical symp…

PURPOSE: To identify risk factors that predict the persistence of noncyclical pelvic pain in patients with endometriosis despite receiving hormone therapy. METHODS: This retrospective study examined 164 patients with histopathologically co…

OBJECTIVE: To develop best practice guidelines under the auspices of the CNGOF and Convergences PP for the management of pain associated with endometriosis. METHOD: We organised a literature review and a formal expert consensus. A multidis…

OBJECTIVE: To develop a machine learning method for the automatic recognition of endometriosis lesions during laparoscopic surgery and evaluate its feasibility and performance. DESIGN: Collecting and annotating surgical videos and training…

OBJECTIVES: A recent study has shown that myofibroblasts are primed for apoptosis when survival pathways are inhibited under fibrosis. This knowledge of apoptosis priming led to the development of methods to induce apoptosis specifically in…

OBJECTIVE: To demonstrate the laparoscopic management of bilateral round ligament endometriosis. SETTING: A tertiary referral center specializing in minimally invasive gynecologic surgery. PARTICIPANTS: An obese woman who had previously u…

This group was formed out of the conviction that endometriosis research has not progressed at a pace in proportion to disease severity and the negative impact on women's quality of life. Furthermore, advancement in our understanding of this…

OBJECTIVE: The purpose of this paper is to call for a nationwide study to assess the prevalence and incidence of women health problems related to menstrual disorders and severe pelvic pain. RATIONALE: The exact prevalence and incidence of …

BACKGROUND: Endometriosis is often described as a progressive disease beginning with menarche and menstrual bleeding. However, this is controversial, as the origin of the disease remains unknown. The objective of this study was to investiga…

The main objective of this study was to review and perform a meta-analysis of current literature on the use of indocyanine green for sentinel lymph node detection in pelvic gynecologic cancer. We included all studies focusing on indications…

BACKGROUND: Management of endometriosis should be based on the best available evidence. The pyramid of evidence reflects unbiased observations analysed with traditional statistics. Evidence-based medicine (EBM) is the clinical interpretatio…