Wen Zhang

ORCID: 0000-0002-4973-1168 · 30 papers in corpus
other 2026
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2026.08.012

OBJECTIVE: To investigate the complementary roles of rectal magnetic resonance imaging and endoscopic ultrasound in the preoperative assessment of rectal deep endometriosis (DE). DESIGN: Retrospective, cross-sectional study. SETTING: Shen…

observational 2025
Heliyon ·doi:10.1016/j.heliyon.2024.e40902

BACKGROUND: Growing evidence suggests that environmental pollutants exert a detrimental impact on female fertility. Among these pollutants, volatile organic compounds (VOCs), easily encountered in the environment, have garnered significant …

other 2025
Frontiers in endocrinology ·doi:10.3389/fendo.2025.1625638

OBJECTIVE: This study explores the metabolic profiles in the peripheral blood of infertile patients with adenomyosis (ADM) to identify key metabolites affecting pregnancy outcomes in these patients undergoing frozen embryo transfer (FET). O…

observational 2025
BMC women's health ·doi:10.1186/s12905-025-03759-3

BACKGROUND: Despite proposed mechanisms hypotheses, the etiology of adenomyosis remains unclear. The limited efficacy of current therapeutic approaches may stem from insufficient understanding of its pathobiological underpinnings and the pr…

observational 2024
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1458527

OBJECTIVE: We investigated whether the addition of a luteal phase support drug benefits pregnancy and perinatal outcomes in modified natural-cycle frozen-thawed embryo transfer (mNC-FET) for women up to the age of 35 years. METHODS: We ana…

observational 2023
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-023-01210-2

To explore the association between uterine volume and in vitro fertilization (IVF) reproductive outcomes of infertile patients with adenomyosis, we performed a retrospective cohort study of infertile patients with adenomyosis who underwent …

case-report 2023
World journal of clinical cases ·doi:10.12998/wjcc.v11.i18.4326

BACKGROUND: Lung endometriosis is an extremely rare gynecological disease. Current literature reports suggest that the majority of patients will present with only generic symptoms, such as hemoptysis, pneumothorax, and hemopneumothorax, whi…

rct 2023
Clinical pharmacology in drug development ·doi:10.1002/cpdd.1215

Dienogest is effective in reducing endometriosis-related pain symptoms. This study aims to investigate and compare the pharmacokinetic profiles and safety of test formulations to reference formulations of dienogest in healthy Chinese female…

case-report 2023
Current medical research and opinion ·doi:10.1080/03007995.2023.2192609

OBJECTIVE: To explore a non-routine method of oocyte retrieval in patients with difficulty in obtaining oocytes via the vagina during a cycle of in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI)-embryo transfer (ET). MET…

observational 2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.837731

BACKGROUND: With the increasing use of frozen embryo transfer (FET), the best endometrial preparation protocol is continuously being discussed. The hormone replacement therapy (HRT) cycle and letrozole-induced ovulation (L-OI) cycle are ava…

observational 2022
Annals of translational medicine ·doi:10.21037/atm-21-6247

BACKGROUND: Whether gonadotrophin-releasing hormone agonist (GnRH-a) pretreatment before transferring frozen-thawed embryos (FETs) could improve the clinical outcome of adenomyosis-associated infertile patients with 56 cm3 ≤ uterine volume …

observational 2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.986809

OBJECTIVE: To evaluate the optimal waiting period for frozen-thawed embryo transfer (FET) after hysteroscopic polypectomy (HSC-P). DESIGN: Retrospective cohort. SETTING: University-affiliated hospital. PATIENTS: All patients included in …

observational 2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.865358

BACKGROUND: Adenomyosis is commonly encountered in infertile women; however, it is still unclear whether adenomyosis has a detrimental effect on in vitro fertilization and embryo transfer (IVF-ET) outcomes. METHOD: We enrolled 1146 patient…

observational 2022
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2022.09.021

RESEARCH QUESTION: What is the effect of adenomyosis types on IVF and embryo transfer (IVF-ET) after ultra-long gonadotrophin-releasing hormone (GnRH) agonist protocol? DESIGN: Patients who underwent the first cycle of IVF-ET with ultra-lo…

case-report 2021
·doi:10.21203/rs.3.rs-141435/v1

Abstract Background: Lung endometriosis is an extremely rare gynecological disease. Literature reports suggest that most patients will show generic symptoms such as hemoptysis, pneumothorax, and hemopneumothorax, which can often result in …

observational 2021
·doi:10.1016/j.gocm.2021.07.007

Abstract Background Endometriosis is a chronic disease that affects women in reproductive age, and adenomyosis was known as “endometriosis in the uterus”. Endometriosis is an immune-dysfunction-related disease, contributing to the diversity…

observational 2021
Frontiers in endocrinology ·doi:10.3389/fendo.2021.795254

Unlike poor ovarian response, despite being predicted to be normal responders based on their ovarian reserve markers, many patients respond suboptimally to ovarian stimulation. Although we can improve the number of retrieved oocytes by incr…

observational 2020
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2020.10.002

RESEARCH QUESTION: What is the relationship between uterine volume before frozen-thawed embryo transfer (FET) and reproductive outcomes among adenomyosis patients? DESIGN: Clinical characteristics and outcomes of adenomyosis patients under…

lab-animal 2020
Journal of pain research ·doi:10.2147/jpr.s232313

BACKGROUND: Pain sensitization processing in the central nervous system may be related to endometriosis-associated pain in patients. The purpose of this study was to understand the alterations in the abnormal pain response in central brain …

observational 2020
Archives of gynecology and obstetrics ·doi:10.1007/s00404-020-05657-5

BACKGROUND: Ovarian endometriosis is the most frequent type of endometriosis. Despite the use of surgery and medication, many patients suffer from recurrence within near future. Currently, there are no effective clinical characteristics ava…

case-report 2020
·doi:10.21203/rs.3.rs-135229/v1

Abstract Background:Lung endometriosis is an extremely rare gynecological disease. Literature reports suggest that most patients will show generic symptoms such as hemoptysis, pneumothorax, and hemopneumothorax, which can often result in m…

2020
·doi:10.2147/jpr.s262383

[This corrects the article DOI: 10.2147/JPR.S232313.].

observational 2020
Annals of translational medicine ·doi:10.21037/atm-20-1309

BACKGROUND: Endometriosis is a benign, chronic, gynecological disease which affect the women in reproductive age. The dysfunction of immune system is associated with endometriosis and the diversity of microbiota in genital tract. According …

lab-animal 2019
Annals of translational medicine ·doi:10.21037/atm.2019.11.73

BACKGROUND: Endometriosis (EM) is a common gynecological disease in women of reproductive age. These patients in approximately 80% suffer the various degree pain. This study will investigate synergistically the mechanism of the higher-posit…

other 2019
The Journal of international medical research ·doi:10.1177/0300060518795582

OBJECTIVE: This study was performed to investigate the diagnostic accuracy of frozen section (FS) of mucinous borderline ovarian tumors (mBOTs) and the diagnostic value of various risk factors for misdiagnosis. METHODS: Patients with eithe…