Yu-Qing Fang — Endo Lab

lab-animal 2025

AlkB Homolog 5 Regulates Hexokinase 2-Mediated Glycolysis and Participates in the Progression of Endometriosis

FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202500614r

Endometriosis is a common gynecological endocrine disease with unclear pathogenesis. Evidence suggests enhanced aerobic glycolysis in ectopic endometrium of endometriosis. The role of N6-methyladenosine (m6A) modification in female reproduc…

lab-animal 2025

Estradiol regulates MBOAT1-mediated ferroptosis and participates in the progression of endometriosis

Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.70069

AIM: Endometriosis is an estrogen-dependent disease with unclear pathogenesis. Recent evidence suggests that ferroptosis plays an important role in the development of endometriosis. In this study, we aimed to explore whether membrane-bound …

rct 2024

N-acetylcysteine supplementation improves endocrine-metabolism profiles and ovulation induction efficacy in polycystic ovary syndrome

Journal of ovarian research ·doi:10.1186/s13048-024-01528-8

BACKGROUND: Polycystic ovary syndrome (PCOS) affects 6-20% of women worldwide, with insulin resistance and hyperinsulinemia occurring in 50-70% of patients. Hyperinsulinemia exacerbates oxidative stress, contributing to PCOS pathogenesis. N…