Orhan Bukulmez

No ORCID on file · 12 papers in corpus
observational 2021
Frontiers in endocrinology ·doi:10.3389/fendo.2021.669507

BACKGROUND: Early cumulus cell removal combined with early rescue intracytoplasmic sperm injection (ICSI) has been widely practiced in many in vitro fertilization (IVF) centers in China in order to avoid total fertilization failure. However…

other 2020
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00093-6

Although it is well appreciated that ovarian stimulation protocols for in vitro fertilization (IVF) alter endometrial receptivity, the precise cellular mechanisms are not known. To gain insights into potential mechanisms by which different …

other 2018
Systems biology in reproductive medicine ·doi:10.1080/19396368.2018.1557761

Premature follicular rupture during in vitro fertilization (IVF) is a well-known culprit for cycle cancellation. We sought to evaluate whether a single oral dose of ibuprofen will have an effect on the follicular fluid (FF) levels of inflam…

lab-animal 2017
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117691145

BACKGROUND: Androgenic compounds have been implicated in induction of endometrial atrophy yet the mechanisms of androgen effects on human endometrium have not been well studied. We hypothesized that androgens may promote their endometrial e…

2016

A number of microRNAs (miRNAs), including miR-200 family, are aberrantly expressed in endometriosis and endometrial cancer. Hereweassessed theexpression and functional aspectsofmiR-200c inendometrial tissues (N 52) fromnormal endometrial bi…

2016

A number of microRNAs (miRNAs), including miR-200 family, are aberrantly expressed in endometriosis and endometrial cancer. Hereweassessed theexpression and functional aspectsofmiR-200c inendometrial tissues (N 52) fromnormal endometrial bi…

lab-animal 2013

ENDOMETRIOSIS IS AN estrogen-dependent disease associated with enhanced aromatase expression and local estrogen production in endometriotic tissues (1–3). Although retrograde menstruation with subsequent implantation and growth of endometri…

other 2012
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112438448

A number of microRNAs (miRNAs), including miR-200 family, are aberrantly expressed in endometriosis and endometrial cancer. Here we assessed the expression and functional aspects of miR-200c in endometrial tissues (N = 52) from normal endom…

lab-animal 2008
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2008-0248

CONTEXT: Up-regulation of aromatase expression in endometrial cells disseminated into the peritoneal cavity may enhance their survival via local estrogen synthesis, which may lead to endometriosis. The factors that mediate induction of arom…

lab-animal 2008
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719108324132

MicroRNAs (miRNAs) which regulate gene expression stability displayed an aberrant expression profile in ectopic endometrium (ECE) as compared to eutopic (EUE) and normal endometrium (NE). We assessed the expression of miR-17-5p, miR-23a, mi…

other 2007
Endocrinology ·doi:10.1210/en.2007-0665

Aberrant up-regulation of aromatase in eutopic endometrium and implants from women with endometriosis has been reported. Aromatase induction may be mediated by increased cyclooxygenase-2 (COX-2). Recently, we demonstrated that progesterone …

nonrandomized-trial 2006
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.06.041

OBJECTIVE: To determine whether women with hydrosalpinx would have diminished endometrial HOXA10 expression and whether salpingectomy would reverse HOXA10 suppression. The homeobox gene HOXA10 is a transcription factor that is necessary for…