Hiroshi Fujiwara

ORCID: 0000-0003-3098-9406 · 15 papers in corpus
case-report 2024
Molecular and clinical oncology ·doi:10.3892/mco.2024.2748

Although adenomyosis is a benign uterine disease, it can turn malignant in rare instances. Cystic adenomyosis is a rare variation of adenomyosis, arising from which 8 cases of clear cell carcinoma have been reported. However, to the best of…

lab-animal 2023
Cancer medicine ·doi:10.1002/cam4.5824

BACKGROUND: Since the human papillomavirus vaccines do not eliminate preexisting infections, nonsurgical alternative approaches to cervical intraepithelial neoplasia (CIN) have been required. We previously reported that FOXP4 (forkhead box …

lab-animal 2023
Biomolecules ·doi:10.3390/biom13020193

Uterine leiomyomas are smooth-muscle tumors originating in the myometrium and are the most common pelvic tumors in women of reproductive age. Symptomatic tumors may result in abnormal uterine bleeding, bladder dysfunction, pelvic discomfort…

other 2020
Nutrients ·doi:10.3390/nu12051294

There are growing concerns that poor dietary behaviors at young ages will increase the future risk of chronic diseases in adulthood. We found that female college students who skipped breakfast had higher incidences of dysmenorrhea and irreg…

lab-animal 2020
Scientific reports ·doi:10.1038/s41598-020-65299-0

Periodic myometrial contraction is one of the important uterine functions to achieve embryo implantation and parturition. Although it is well-known that the mammalian myometrium is composed of longitudinal (outer) and circular (inner) layer…

observational 2020
Diagnostics (Basel, Switzerland) ·doi:10.3390/diagnostics10070476

Inadequate dietary habits in youth are known to increase the risk of onset of various diseases in adulthood. Previously, we found that female college students who skipped breakfast had higher incidences of dysmenorrhea, suggesting that brea…

observational 2020
BMC cancer ·doi:10.1186/s12885-020-6549-5

BACKGROUND: We previously reported that tamoxifen (TAM)-induced ovarian hyperstimulation (OHS) is associated with high serum concentrations of estradiol in premenopausal women with breast cancer. To investigate risk factors for TAM-induced …

lab-animal 2019
Current developments in nutrition ·doi:10.1093/cdn/nzy093

BACKGROUND: We previously reported that skipping breakfast is associated with menstrual disorders of female college students during postadolescent maturation. OBJECTIVE: In this study, we investigated the effects of meal timing during circ…

2018
·doi:10.1016/j.jri.2018.09.027
observational 2017
PloS one ·doi:10.1371/journal.pone.0188641

Although histological grade and muscular invasion are related to the malignant behaviors of endometrial endometrioid carcinoma, lymphatic and/or distant metastases are unexpectedly encountered, even in patients in the low-risk group. To re-…

lab-animal 2016
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12609

PROBLEM: The human endometrium periodically breaks down and regenerates. As platelets have been reported to contribute to the tissue remodeling process, we examined the possible involvement of platelets in endometrial regeneration. METHOD …

lab-animal 2014
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.02.005

OBJECTIVE: To investigate the impact of estrogen contained in oral contraceptives (OCs) on the action of progestin on ovarian endometrioma epithelial cells. DESIGN: Experimental in vitro study and immunohistochemical analysis. SETTING: Un…

review 2004
Reproductive medicine and biology ·doi:10.1111/j.1447-0578.2004.00074.x

A number of biologically active peptides have been proposed to regulate function and differentiation of reproductive organs in an autocrine and/or paracrine fashion. Regulation of the local concentrations of these peptides is one of the imp…

case-report 2003
Human Reproduction ·doi:10.1093/humrep/deg076

A clinical case that suggested the involvement of blood coagulation cascades in the inflammation reaction induced by leakage of ovarian endometriotic cysts was encountered. Here, a rapid elevation in plasma D-dimer level (119.6 micro g/ml) …

other 1992
Human Reproduction ·doi:10.1093/oxfordjournals.humrep.a137849

Indirect immunofluorescence staining revealed that endometrial stromal cells (ESC) in the ectopic endometrium of patients with endometriosis or adenomyosis expressed aminopeptidase N/cluster of differentiation (CD) 13 antigen and neutral en…