Zhenzhen Zhang

ORCID: 0000-0002-0934-4796 · 11 papers in corpus
lab-animal 2025
Inflammation research : official journal of the European Histamine Research Society ... [et al.] ·doi:10.1007/s00011-025-02010-x

Endometriosis, a persistent inflammatory disease, is associated with pelvic or abdominal pain. The immune system and sensory nervous system show a synergistic effect on regulation of pain. In particular, Interleukin-33 (IL-33) is released a…

observational 2025
Drug design, development and therapy ·doi:10.2147/dddt.s521554

PURPOSE: Progestin-primed ovarian stimulation (PPOS) has been widely employed in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles. In recent years, letrozole (LE) combined with medroxyprogesterone acetate (MPA) has …

other 2024
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan ·doi:10.19852/j.cnki.jtcm.2024.06.004

OBJECTIVE: To investigate the mechanism of Bushen Huoxue decoction (, BSHXD) to treat endometriosis-induced infertility. MEDHODS: The main compounds of BSHXD were determined by high performance liquid chromatography-mass spectrometry (HPLC…

lab-animal 2024
Journal of ethnopharmacology ·doi:10.1016/j.jep.2024.118724

ETHNOPHARMACOLOGICAL RELEVANCE: Wenshen Xiaozheng Tang (WXT), a traditional Chinese medicine (TCM) decoction, is effective for treating endometriosis. However, the effect of WXT on endometrium-derived mesenchymal stem cells (eMSCs) which pl…

observational 2020
Frontiers in physiology ·doi:10.3389/fphys.2020.491892

OBJECTIVES: To evaluate the effect of dyslipidemia on the incidence of moderate and severe Ovarian hyperstimulation syndrome (OHSS) in the duration of assisted reproduction technique (ART). METHODS: The study included 233 moderate and seve…

lab-animal 2019
Cell communication and signaling : CCS ·doi:10.1186/s12964-019-0361-3

BACKGROUND: Endometriosis, characterized by the presence of functional endometrial tissues outside the uterus, is one of the most common gynecological disorders. Endometrial mesenchymal stem cells (MSCs) are crucial for the occurrence and d…

lab-animal 2019
Stem cells international ·doi:10.1155/2019/6183796

During the development of endometriosis, the presence of fibrotic tissues in and surrounding endometriotic lesions may lead to subsequent adhesion, anatomic distortion, and chronic pain. Therefore, studies aimed at clarifying the underlying…

lab-animal 2016
Journal of ethnopharmacology ·doi:10.1016/j.jep.2016.07.019

ETHNOPHARMACOLOGICAL RELEVANCE: Wenshen Xiaozheng Tang (WXT), a traditional Chinese medicine prescription, exerted a good therapeutic effect on endometriosis. However, the underlying mechanism is unclear. In the present study, we sought to …

nonrandomized-trial 2014
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

OBJECTIVE: To observe the therapeutic efficacy and safety of gonadotropin-releasing hormone agonist (GnRHa) combined Wenshen Xiaozheng Decoction (WXD) in auxiliary treating endometriosis after laparoscopy. METHODS: One hundred and thirty-f…

other 2014
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.10.050

OBJECTIVE: To investigate the balance between regulatory T cells (Treg) and T-helper 17 cells (T(H)17) in peripheral blood and uteri of women with adenomyosis (AM), and to evaluate their potential correlation with dysmenorrhea and CA-125 le…

lab-animal 2013
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113483008

The objective of this study is to investigate the effect of Wenshen Xiaozheng Tang (WXT) on the development of endometriosis in a rat model. Sprague-Dawley rats in which endometriotic implants were induced were divided randomly into 3 group…