Chao Huang — Endo Lab

2025

Development of a non-invasive urine test for deep endometriosis: results from a prospective observational study.

·doi:10.22541/au.176603595.53494581/v1

Objective: Endometriosis affects 1 in 10 women of reproductive age worldwide, yet there is no accurate non-invasive diagnostic test that would help triage patients into the best practice treatment pathway. We aimed to identify a diagnostic …

other 2025

MEGF8-driven metabolic reprogramming and immune evasion define a high-risk subtype of endometriosis-associated ovarian cancer

American journal of translational research ·doi:10.62347/AOPY5249

OBJECTIVE: Endometriosis increases ovarian cancer (OC) risk through genetic mutations, chronic inflammation, and hormonal dysregulation, yet the underlying molecular pathways remain underexplored. This study aims to identify endometriosis-a…

other 2024

Identification and verification of diagnostic biomarkers for deep infiltrating endometriosis based on machine learning algorithms

Journal of biological engineering ·doi:10.1186/s13036-024-00466-9

This study addresses the challenges in the early diagnosis of deep infiltrating endometriosis (DIE) by exploring the potential role of the deubiquitinating enzyme USP14. By analyzing the GSE141549 dataset from the Gene Expression Omnibus (G…

review 2018

HOXA11-AS: a novel regulator in human cancer proliferation and metastasis

OncoTargets and therapy ·doi:10.2147/ott.s166961

Multiple studies have demonstrated that lncRNAs extensively participate in human cancer proliferation and metastasis. Epigenetic modification, transcriptional and posttranscriptional regulatory mechanisms are involved in lncRNA-led tumorige…