Shay M. Freger

ORCID: 0000-0001-5534-3965 · 36 papers in corpus
review 2024
Therapeutic advances in reproductive health ·doi:10.1177/26334941241277759

Endometriosis is a prevalent gynecological disease, leading to chronic pain and inflammation, affecting 1 in 10 individuals presumed female at birth. The diagnostic journey is often arduous, marked by neglect of the right diagnosis and prol…

diagnostic-accuracy 2024
·doi:10.1002/uog.29012

Transvaginal ultrasound (TVS) is crucial for diagnosing endometriosis, guided by the International Deep Endometriosis Analysis (IDEA) guidelines. While TVS excels in diagnosing ovarian (OE) and deep endometriosis (DE), superficial endometri…

meta-analysis 2024
Fertility and sterility ·doi:10.1016/j.fertnstert.2023.12.008

Endometriosis affects 1 in 9 women and those assigned female at birth. However, it takes 6.4 years to diagnose using the conventional standard of laparoscopy. Noninvasive imaging enables a timelier diagnosis, reducing diagnostic delay as we…

diagnostic-accuracy 2024
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology ·doi:10.1002/uog.27492

OBJECTIVE: To determine the diagnostic test accuracy of transvaginal ultrasound (TVS) using a standardized technique for the diagnosis of deep endometriosis (DE) of the uterosacral ligaments (USLs) and adjacent torus uterinus (TU). METHODS…

meta-analysis 2023
Fertility and sterility ·doi:10.1016/j.fertnstert.2023.12.017

Endometriosis affects 1 in 9 women, taking 6.4 years to diagnose using conventional laparoscopy. Non-invasive imaging enables timelier diagnosis, reducing diagnostic delay, risk and expense of surgery. This review updates literature explori…

diagnostic-accuracy 2023
·doi:10.1002/uog.26376

The uterosacral ligaments (USLs) and torus uterinus (TU) are common sites for deep endometriosis (DE) but are challenging to diagnose through transvaginal ultrasound (TVS). Anatomical distortion caused by severe endometriosis, including pou…

observational 2023
·doi:10.1002/uog.26380

An up-to-date description of ovarian and deep endometriosis distribution is necessary as the diagnostic algorithm now includes ultrasound as a highly specific diagnostic test. The primary objective was to describe ovarian/deep endometriosis…

observational 2023
·doi:10.1002/uog.26519

The primary objective of this study is to establish whether ultrasound (US) diagnosis of endometriosis affects patient decision-making on treatment options. Secondary objectives include determining: 1) patient comfort of endometriosis US; 2…

2023
·doi:10.5256/f1000research.154963.r208441
review 2021
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2021.05.022

Endometriosis is a chronic oestrogen-dependent gynaecological disorder characterized by non-menstrual pelvic pain, infertility and the extrauterine growth of endometrial-like glands and stroma. It has been noted that the eutopic endometrium…

meta-analysis 2020
·doi:10.5772/intechopen.91002

Endometriosis is widely acknowledged to be an estrogen dependent disease or unknown etiology. Recognition that environmental toxicants can bind with and activate the estrogen receptor, dysregulate steroid metabolism and, in some cases, act …