Mengxi Guo

ORCID: 0009-0007-9490-6661 · 3 papers in corpus
lab-animal 2026
Identification of cryosensitive niches and a targetable FOS/AP‑1 program in the human ovarian cortex by single‑cell and spatial transcriptomics
BMC medicine ·doi:10.1186/s12916-026-04757-4

BACKGROUND: The ovary is a vital and dynamic reproductive organ. Ovarian tissue cryopreservation (OTC) plays a vital role in preserving female fertility. However, the cellular subtypes most susceptible to cryoinjury and the molecular mechan…

lab-animal 2023
Overexpression of Pde4d in rat granulosa cells inhibits maturation and atresia of antral follicles to induce polycystic ovary
Biochimica et biophysica acta. Molecular basis of disease ·doi:10.1016/j.bbadis.2023.166869

BACKGROUND: Follicle dysplasia can cause polycystic ovary syndrome, which can lead to anovulatory infertility. This study explored gene(s) that may contribute to polycystic ovary syndrome. METHODS: Three animal models of polycystic ovary s…

case-report 2022
Concurrent Ovarian and Tubal Ectopic Pregnancy After IVF-ET: Case Report and Literature Review
Frontiers in physiology ·doi:10.3389/fphys.2022.850180

Ovarian pregnancy (OP) coupled with tubal ectopic pregnancy is rare. We present a case of coexistent ovarian and tubal ectopic pregnancies in the same adnexa resulting from in vitro fertilization and embryo transfer (IVF-ET) for tubal occlu…