Kailu Liu

No ORCID on file · 3 papers in corpus
lab-animal 2026
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome
Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-026-06134-z

Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder and a major cause of female infertility. While epigenetic dysregulation, notably DNA methylation, has been recognized as a key driver of PCOS pathogenesis, the specific involv…

other 2024
Differential expression of follicular fluid exosomal microRNA in women with diminished ovarian reserve
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-024-03037-5

PURPOSE: Decreased ovarian reserve function is mainly characterized by female endocrine disorders and fertility decline. Follicular fluid (FF) exosomal microRNAs (miRNAs) have been shown to regulate the function of granulosa cells (GCs). Th…

lab-animal 2023
Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome
Clinical epigenetics ·doi:10.1186/s13148-023-01487-9

Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder characterized by chronic low-grade inflammation. Previous studies have demonstrated that the gut microbiome can affect the host tissue cells' mRNA N6-methyladenosine (m…