Wollborn L

ORCID: 0009-0007-3543-1643 · 3 papers in corpus
other 2026
A lasso-based model combining miRNA and clinical variables predicts future risk of breast and ovarian cancer
Scientific reports ·doi:10.1038/s41598-026-45020-3

Hereditary breast and ovarian cancer syndrome (HBOC) is principally caused by germline mutations in BRCA1 and BRCA2. However, most women with HBOC are undiagnosed, and some patients meeting clinical criteria for HBOC will have no identifiab…

observational 2025
Effects of Clinical Covariates on Serum miRNA Expression among Women without Ovarian Cancer
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.epi-23-1355

BACKGROUND: Serum miRNAs are potential biomarkers for ovarian cancer; however, many factors may influence miRNA expression. To understand potential confounders in miRNA analysis, we examined how sociodemographic factors and comorbidities, i…

diagnostic-accuracy 2024
Serum miRNA improves the accuracy of a multivariate index assay for triage of an adnexal mass
Gynecologic Oncology ·doi:10.1016/j.ygyno.2024.08.008

OBJECTIVE: To determine whether a multimodal assay combining serum microRNA with protein biomarkers and metadata improves triage assessment of an adnexal mass. METHODS: Serum samples from 468 training subjects (191 cancer cases and 277 ben…