Xiao Xu

OBJECTIVE: To evaluate the association between medication for opioid use disorder (MOUD) and surgical complications and health care utilization among patients with opioid use disorder (OUD) undergoing hysterectomy. METHODS: Using MarketSca…

Opportunistic salpingectomy reduces ovarian cancer risk. To examine heterogeneity among physicians in their adoption of opportunistic salpingectomy in hysterectomy practice, we identified 33,401 non-pregnant patients aged 18 to 49 years in …

Existing evidence shows the importance of circulating cytokines in studying female reproductive system dysfunction. Endometriosis (EM) is thought to be associated with multiple immune cytokines, but its causality has not been proven. Utilis…

BACKGROUND: Since professional societies recommended counseling patients about opportunistic salpingectomy for ovarian cancer risk reduction, use of opportunistic salpingectomy has increased overall. However, physicians varied in their adop…

OBJECTIVES: To examine variation in physician adoption of opportunistic salpingectomy (OS) for patients undergoing tubal sterilization. STUDY DESIGN: Using the Premier Healthcare Database, we identified patients age 18-49 undergoing postpa…

BACKGROUND: While endometriosis (EM) has been previously associated with multiple immune factors, the causal relationship underlying these associations remains unclear. OBJECTIVE: In this study, Two-sample Mendelian randomization (MR) meth…

OBJECTIVE: No consensus currently exists regarding patient-reported outcome measure (PROM) instruments. This structured review was conducted to identify the PROMs used by randomized controlled trials (RCTs) that evaluated surgical treatment…

BACKGROUND: Following a 2014 safety warning (that laparoscopic power morcellation may increase tumor dissemination if patients have occult uterine cancer), hysterectomy practice shifted from laparoscopic to abdominal approach. This avoided …

BACKGROUND: Safety warnings about power morcellation in 2014 considerably changed hysterectomy practice, especially for laparoscopic supracervical hysterectomy that typically requires morcellation to remove the corpus uteri while preserving…

BACKGROUND: Occult uterine cancer at the time of benign hysterectomy poses unique challenges in patient care. There is large variability and uncertainty in estimated risk of occult uterine cancer in the literature and prior research often d…

INTRODUCTION: To inform proper surgical planning and policy discussion regarding uterine power morcellation, this study estimated the prevalence of occult uterine cancer in a large population-based sample of women undergoing hysterectomy fo…

A prospective, randomized, placebo-controlled study was conducted in a baboon model to determine if a thiazolidinedione agonist of peroxisome proliferator-activated receptor-gamma, pioglitazone, can impede the development of endometriosis. …