Meizhen Huang

ORCID: 0000-0003-4996-4276 · 4 papers in corpus
observational 2025
Correlation of the sperm DNA fragmentation index with semen parameters and its impact on fresh embryo transfer outcomes-a retrospective study
PeerJ ·doi:10.7717/peerj.19451

PURPOSE: To evaluate the relationships between the sperm DNA fragmentation index (DFI) and semen parameters and its application in fresh embryos via in vitro fertilization and transfer. METHODS: A retrospective propensity score matching (P…

other 2024
The role of mitochondrial DNA copy number in female infertility: a bidirectional two-sample Mendelian randomization study
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2024.2444380

BACKGROUND: Previous studies on the impact of mitochondrial DNA (mtDNA) copy number on female infertility were limited and inconsistent. METHODS: The causal relationship between mtDNA copy number and female infertility was evaluated using …

lab-animal 2015
Tanshinone IIA inhibits the proliferation, migration and invasion of ectopic endometrial stromal cells of adenomyosis via 14-3-3ζ downregulation
Archives of gynecology and obstetrics ·doi:10.1007/s00404-015-3766-2

BACKGROUND: Adenomyosis is a specific subtype of endometriosis and recent evidences have indicated that Tanshinone IIA (TSIIA) might be a potential therapeutic option for endometriosis. Meanwhile, endometrial stromal cells (ESCs) of adenomy…

other 2014
Frequent POLE1 p.S297F mutation in Chinese patients with ovarian endometrioid carcinoma
Mutation research ·doi:10.1016/j.mrfmmm.2014.01.003

The catalytic subunit of DNA polymerase epsilon (POLE1) functions primarily in nuclear DNA replication and repair. Recently, POLE1 mutations were detected frequently in colorectal and endometrial carcinomas while with lower frequency in sev…