Zijie An,1,* Yanqing Gong,2,* Xuedan Deng,1,* Yong Xie1,3 1School of Clinical Medicine, Guangdong Medical University, Zhanjiang, Guangdong, People’s Republic of China; 2The Second Clinical Medical School, Southern Medical Univer…
BACKGROUND: Endometriosis is a chronic estrogen-dependent inflammatory disease that shares epidemiological and pathological features with endometrial cancer. However, the cellular and genetic mechanisms underlying this association remain un…
The rapid expansion and advancement of nanotechnology have presented potential applications in the diagnosis and treatment of various diseases. In recent years, cerium oxide nanoparticles (CeO2 NPs) have been extensively studied and applied…
BACKGROUND: Live birth rate (LBR) has been associated with ethnicity and race in Europe and the United States. However, the impact of ethnicity on LBR among multiethnic Chinese infertile women has remained unexplored. This study aims to inv…
[This corrects the article DOI: 10.3389/fendo.2025.1687765.].
BackgroundThis study aimed to explore whether an endometrial thickness (EMT) cutoff of 7 mm or 8 mm was more appropriate to define thin endometrium (TE) from the perspective of miscarriage and obstetric-neonatal complications.MethodsWe cond…
RESEARCH QUESTION: Is there a difference in the euploidy status and pregnancy outcomes among patients undergoing preimplantation genetic testing for aneuploidy (PGT-A) inoculated with inactivated severe acute respiratory syndrome coronaviru…
BackgroundJinfeng pills (JFP), a well-known traditional Chinese medicine (TCM) consisted of 9 herbs, benefit Qi, nourish the blood, effectively regulate the menstrual cycle, promote ovulation and improve endometrial thickness and blood flow…
Migraine is a highly prevalent and disabling neurological disorder with multiple hypotheses regarding its pathogenesis. G protein-coupled receptor 30 (GPR30), a member of the G protein-coupled receptor family, was once considered a membrane…
The rapid advances in epigenetic and epitranscriptomic regulatory mechanisms have opened new prospects for precision therapies in various diseases. N-acetyltransferase 10 (NAT10) is currently the only known eukaryotic RNA ac4C acetyltransfe…
Acute pancreatitis (AP) is a common gastrointestinal emergency requiring hospitalization. In recent years, several studies have demonstrated a role for 4-octyl itaconate (4-OI) in anti-inflammatory and oxidative stress injury. However, the …
BACKGROUND: Fibrogenesis is a common pathological feature of endometriotic lesions and contributes to the development of endometriosis-associated chronic pelvic pain and infertility. TGF-β is a critical factor in the induction of fibrogenes…
STUDY QUESTION: What are the impacts of different male infertility factors on embryological, cumulative pregnancy and neonatal outcomes of IVF/ICSI cycles? SUMMARY ANSWER: Some severe male infertility factors, i.e. severe oligoasthenozoosp…
BACKGROUND: This study aims to evaluate the impact of endometriotic cysts and prior ovarian endometriotic cystectomy on ovarian reserve function in women with endometriosis undergoing assisted reproductive technology. METHODS: In this retr…
Abstract Background Postoperative fever (PF) and postoperative bloodstream infections (PBSIs) are common and severe complications following gynecological surgery, yet they receive less focus than surgical site infections. This study aime…
Adenomyosis is a common gynecological disease characterized by the invasion of endometrial glands and stroma into the myometrium of uterus, the pathological mechanism of which remains unclear yet. Disturbed lipid metabolism extensively affe…
OBJECTIVE: This study aimed to assess the impact of inoculation with the inactivated coronavirus disease 2019 (COVID-19) vaccine on the outcomes of in vitro fertilization and embryo transfer (IVF-ET). METHODS: From January 2021 to December…
BACKGROUND: Fibrogenesis within ovarian endometrioma (endometrioma), mainly induced by transforming growth factor-β (TGF-β), is characterized by myofibroblast over-activation and excessive extracellular matrix (ECM) deposition, contributing…
Perfluoroalkyl and polyfluoroalkyl substances (PFASs), widely utilized in various industries, may pose potential reproductive well-being risks. However, the research on the impact of PFAS exposures on pregnancy and live birth rates remains …
BACKGROUND: Growth hormone (GH) could improve the outcomes of in vitro fertilization and embryo transfer (IVF-ET) in patients with decreased ovarian reserve (DOR), but which age group will benefit the most has remained controversial. This s…
Currently, the precise and detailed anatomical data of the normal uterus, especially the myometrium thickness in various parts of the uterus, are lacking. This study aims to provide normal references for uterine size in healthy reproductive…
Previous studies have screened key candidate genes for litter size in sheep, including fibrillin-1 (FBN1), family with sequence similarity 184 member B (FAM184B) and zinc finger and AT-hook domain containing (ZFAT). Therefore, it is necessa…
PURPOSE: To analyze the level of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) in follicle fluid (FF) and granulosa cells (GCs) derived from young patients with low prognosis for in vitro fertilization and…
AbstractCyperi rhizoma (CR) has traditionally been used to treat endometriosis (EMS), but its molecular mechanism remains unclear. To address this, we used a multi-faceted approach that included analysis of GEO datasets, network pharmacolog…