Ayako Muraoka

ORCID: 0000-0003-2203-0844 · 18 papers in corpus · active 2018-2026

Study types

  • article 11
  • other 4
  • preprint 1
  • rct 1
  • review 1

Condition tags

  • endometriosis 16
  • mesh:D004715 8
  • endometrioma 4
  • infertility 4
  • dysmenorrhea 2
  • die_deep_infiltrating 1
  • adenomyosis 1
  • bladder_endometriosis 1
article 2026
·doi:10.1038/s43856-026-01704-5

Endometriosis is defined as the ectopic proliferation of endometrial cells. Aberrant signal transduction is present in ectopic endometriotic lesions, and bacteria also contributes to the development of endometriosis by transmitting pathogen…

other 2025
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01381-4

BACKGROUND: Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertil…

article 2025
·doi:10.1016/j.heliyon.2025.e44099

Abstract Extracellular vesicles (EVs) are secreted from mammalian cells and bacteria and are involved in disease pathogenesis. Recently, bacterial factors have been linked to the pathogenesis of endometriosis. Therefore, identifying host-ba…

other 2024
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1442684

INTRODUCTION: Endometriosis can cause of infertility, and evaluation methods for predicting clinical pregnancy outcomes are desired. Extracellular vesicles (EVs) exist in blood and it contains small non-coding RNAs (ncRNAs) that may reflect…

review 2023
iScience ·doi:10.1016/j.isci.2023.108739

The pathogenesis of endometriosis is a complex process, and recent research has introduced novel hypotheses in this field. This review summarizes recent studies on the pathogenesis of endometriosis. We focused on several classical hypothese…

article 2023

Retrograde menstruation is a widely accepted cause of endometriosis. However, not all women who experience retrograde menstruation develop endometriosis, and the mechanisms underlying these observations are not yet understood. Here, we demo…

other 2023
Science translational medicine ·doi:10.1126/scitranslmed.add1531

Retrograde menstruation is a widely accepted cause of endometriosis. However, not all women who experience retrograde menstruation develop endometriosis, and the mechanisms underlying these observations are not yet understood. Here, we demo…

article 2023
Reproductive medicine and biology ·doi:10.1002/rmb2.12536

Abstract Purpose This study aimed to investigate whether serum leucine‐rich α2‐glycoprotein (LRG) is a useful diagnostic biomarker for endometriosis, including the evaluation of treatment efficacy and exploration of LRG production in endome…

article 2023
Reproductive biology ·doi:10.1016/j.repbio.2023.100821
article 2022
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-022-00924-3

Abstract Background Endometriosis is a complex syndrome characterized by an estrogen-dependent chronic inflammatory process that affects 10% of women of reproductive age. Ovarian endometriosis (OE) is the most common lesion in endometriosis…

preprint 2021
·doi:10.21203/rs.3.rs-1062370/v1

Abstract Background Endometriosis is a complex syndrome characterized by an estrogen-dependent chronic inflammatory process that affects 10% of women of reproductive age. Ovarian endometriosis (OE) is the most common lesion in endometriosis…

rct 2021
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00866-2

BACKGROUND: Ovarian endometrioma is a common gynecological disease that is often treated with surgery or hormonal treatment. Ovarian cystectomy, a surgical procedure for ovarian endometrioma, can result in impaired ovarian reserve. METHODS…

article 2020
·doi:10.5180/jsgoe.36.1_185

Appendiceal intussusception secondary to endometriosis is extremely rare. We report a case of left ovarian endometriosis with endometriosis-induced appendiceal intussusception in a 42-year-old woman presenting with rectal bleeding and left-…

article 2020
F&S science ·doi:10.1016/j.xfss.2020.09.001

Objective To establish and characterize cell lines derived from human endometrial epithelial cells (ECs) and mesenchymal cells (MCs) from patients with and without endometriosis. Design In vitro experimental study. Setting University and na…

other 2020
The American journal of pathology ·doi:10.1016/j.ajpath.2019.09.008

Repeated tissue injury and repair and fibrosis play a pivotal role in endometriosis. Fibrotic tissue consists of extracellular matrix proteins, regulated by transcriptional factors promoting cell proliferation and survival. Periostin is one…

article 2019
Nature communications ·doi:10.1038/s41467-019-13708-y

Uterine adenomyosis is a benign disorder that often co-occurs with endometriosis and/or leiomyoma, and impairs quality of life. The genomic features of adenomyosis are unknown. Here we apply next-generation sequencing to adenomyosis (70 ind…

article 2018
·doi:10.1016/j.fertnstert.2018.07.1098
article 2018
·doi:10.5180/jsgoe.34.2_204

Bladder endometriosis is a rare pelvic dysfunction with painful urination and hematuria.