Ernst Kubista

No ORCID on file · 4 papers in corpus
lab-animal 2010
Administration of betaHCG leads to dose-dependent changes of gene expression signature of endometriotic stromal cells
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2010.01.010

Preliminary studies have shown that systemic beta-human chorionic gonadotrophin (betaHCG) therapy alleviates endometriosis-related chronic pelvic pain. The underlying mechanism, however, is completely unknown. This study has investigated th…

other 2009
Beta-hCG/LH receptor (b-HCG/LH-R) expression is increased in invasive versus preinvasive breast cancer: implications for breast carcinogenesis?
Journal of cancer research and clinical oncology ·doi:10.1007/s00432-008-0458-3

INTRODUCTION: The role of the b-HCG/LH/LH-R system in breast cancer is conflicting. Whereas some reports suggest a protective effect of b-HCG on breast epithelium, vitro studies implicate a role of b-HCG/LH-R in the development and growth o…

other 2008
beta-HCG/LH receptor (beta-HCG/LH-R) expression in eutopic endometrium and endometriotic implants: evidence for beta-HCG sensitivity of endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719108316907

BACKGROUND: Luteinizing hormone (LH) and human chorionic gonadotropin (HCG) target their receptor in gonadal and nongonadal cells to stimulate steroidogenesis and cell growth. The aim of the present study was to investigate the expression o…

observational 2005
Estrogen receptor beta and matrix metalloproteinase 1 are coexpressed in uterine endometrium and endometriotic lesions of patients with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.06.014

OBJECTIVE: To evaluate the local matrix metalloproteinase 1 (MMP-1), estrogen receptor (ER) alpha, and ERbeta protein expression in eutopic and dystopic tissue from patients with endometriosis and to compare the endometrial expression patte…