Jing Zhou

OBJECTIVE: To explore the independent metabolic and ultrasonographic factors associated with clinical pregnancy in patients with polycystic ovary syndrome (PCOS) undergoing frozen-thawed embryo transfer (FET) cycles, develop and validate a …

BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disorder characterized by impaired surfactant clearance due to alveolar macrophage dysfunction. Leuprorelin acetate, a gonadotropin-releasing hormone agonist, is widely us…

OBJECTIVE: Women with premenstrual disorder (PMD) display heightened sensitivity to hormonal changes and may be at risk for psychiatric disorders during other hormonally dynamic periods such as pregnancy and postpartum. While PMD has been l…

OBJECTIVE: Our study aims to establish and validate a diagnostic scoring system for distinguishing malignant cystic ovarian tumors (MCOTs) from benign cystic ovarian tumors (BCOTs). METHODS: The study population was sourced from two indepe…

Endometriosis, the most prevalent cause of infertility, is associated with anatomical distortion leading to adhesions and fibrosis, as well as endocrine abnormalities and immune disorders. This review discusses the mechanisms underlying end…

Endometriosis (EM), also known as Zhengjia in traditional Chinese medicine, is a common disease that significantly impacts women's health. An integrated treatment approach combining traditional Chinese medicine (TCM) and western medicine ha…

Endometriosis (EMS) is defined as the appearance, growth, infiltration, and repeated bleeding of endometrioid tissue (glands and stroma) outside the uterus cavity, which can form nodules and masses. Endometriosis is a chronic inflammatory e…

Recurrent spontaneous abortion (RSA) is a multifactorial disease that seriously affects womens physical and mental health. With the advent of efficient contraception, the trend for women towards later maternity until their thirties or even …

Endometriosis is a chronic inflammatory disease. The immune-checkpoint molecules CD226 and TIGIT play an important role in regulating T cells' function. However, little is known about the proportion and function of CD226 and TIGIT on CD4+ T…

The immune system contributes to the pathophysiology of endometriosis. The role of ThGM cells, which produce granulocyte macrophage-colony-stimulating factor (GM-CSF), in the pathogenesis of endometriosis remains unknown. To analyze the fea…

Microorganisms are ubiquitous in the human body; they are present in various areas including the gut, mouth, skin, respiratory tract, and reproductive tract. The interaction between the microbiome and reproductive health has become an incre…

Effective health interventions are a priority for future infertility research, and effective interventions in patient-centered care are still needed. A multi-center prospective study was conducted in order to investigate the effects of a ph…

ABSTRACT Purpose To evaluate the diagnostic value of Genome Sequencing(GS)in children with epilepsy. Methods We performed GS on 320 Chinese children with epilepsy and interpreted Single Nucleotide Variants (SNVs) and Copy Number Variant (CN…

PURPOSE: To study the therapeutic effects of uterine artery embolization (UAE) on adenomyosis and to investigate the association between uterine blood supply and artery embolization treatment outcomes. METHODS: Using digital subtraction an…

【Objective】To investigate the pathology change of endometriosis(EMs) rats which were treated by human chorionic gonadotropin(HCG).【Method】Twenty-four endometriosis rat models were established and were divided into three groups,then were tre…

OBJECTIVE: Recent studies have shown that the local expression of soluble interleukin (IL) -1 receptor type II (sIL-1 RII) in endometrial tissue of women with endometriosis is decreased, and the depression of IL-1 RII was more significant i…

Objective To establish a dynamic endometriosis nude mouse model that allows noninvasive assessment of lesion implantation and development. Methods Twenty-five female nude mice were devided into subcutaneous group(SC,11mice) and intraperiton…

AIM: To develop a gene therapy vector of interleukin-1 receptor II(IL-1RII) with recombinant adenovirus and express IL-1RII in the eutopic stromal cells of endometriosis(EM). METHODS: Get full length of cDNA with IL-1RII gene was obtained …

OBJECTIVE: To determine the role of interleukin-1 receptor type II (IL-1RII) in the pathogenesis of endometriosis. DESIGN: Cultures of endometrial cells exposed to soluble IL-1RII or the recombinant adenovirus of IL-1RII (rAd-RII). SETTIN…

Objective: To explore the effects of soluble interleukin-1 receptor type Ⅱ (sIL-1RⅡ) on interleukin-1α (IL-1α)-induced expression of IL-8 in eutopic endometrial stromal cells (ESC) from patients with endometriosis (EMs). Methods: ESC from p…