Shanchun Guo

ORCID: 0000-0002-3593-3738 · 3 papers in corpus
review 2012
Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
Biochimica et biophysica acta ·doi:10.1016/j.bbcan.2012.01.002

Significant correlations between obesity and incidence of various cancers have been reported. Obesity, considered a mild inflammatory process, is characterized by a high level of secretion of several cytokines from adipose tissue. These mol…

lab-animal 2011
Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer
PloS one ·doi:10.1371/journal.pone.0021467

High levels of pro-angiogenic factors, leptin, IL-1, Notch and VEGF (ligands and receptors), are found in breast cancer, which is commonly correlated with metastasis and lower survival of patients. We have previously reported that leptin in…

2009
O546 Tricostatin A, a histone deacetylase inhibitor, reduces inflammation and improves thermal hypersensitivity in experimentally induced endometriosis in mice
·doi:10.1016/s0020-7292(09)60919-x