Hirabayashi M

ORCID: 0000-0002-1059-5883 · 2 papers in corpus

lab-animal 2025

GPR75 signaling is dispensable for reproduction but contributes to feeding and body growth in rats on normal chow and is involved in high-fat diet-induced hyperphagia, obesity, and hyperglycemia development

Endocrine journal ·doi:10.1507/endocrj.ej25-0099

GPR75 has emerged as a therapeutic target for obesity following the discovery of a causal relationship between GPR75 variants and reduced body mass index in humans. Herein, we examined whether GPR75 is dispensable for normal feeding, body g…

lab-animal 2021

Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator

Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2009156118

The gonadotropin-releasing hormone (GnRH) pulse is fundamental for mammalian reproduction: GnRH pulse regimens are needed as therapies for infertile women as continuous GnRH treatment paradoxically inhibits gonadotropin release. Circumstant…