BACKGROUND: Primary dysmenorrhea (PDM), as a form of chronic pelvic pain, has a complex pathophysiology involving hormonal factors, central nervous system alterations, and maladaptive pain cognition. Previous neuroimaging studies have demon…
UNLABELLED: Midgut volvulus is a rare finding in adults, especially those without a known history of congenital gastrointestinal abnormalities. This is a case of a 78-year-old man who presented to the Emergency Department (ED) with two week…
Endometriosis is increasingly recognized as a systemic disorder involving complex interactions between nerves and immune cells, driving chronic pain and inflammation beyond the initial theories. Recent breakthroughs highlight aberrant senso…
OBJECTIVE: To investigate the clinical significance of miR-30d-5p and transforming growth factor-β (TGF-β)/Smad2 pathway expression levels in polycystic ovary syndrome (PCOS) patients. METHODS: A total of 82 PCOS patients undergoing their …
OBJECTIVE: This study aims to evaluate and compare the clinical effectiveness of endovascular reintervention vs conservative medical therapy in patients with persistent or recurrent venous-origin chronic pelvic pain (CPP) after initial endo…
Acute pancreatitis (AP) is a frequent inflammatory disorder with outcomes ranging from mild disease to severe forms marked by infection and organ failure. Gut microenvironment disruption and barrier dysfunction are increasingly recognized a…
This study investigates the role of carbohydrate antigen 125 (CA125) in the pathogenesis of systemic lupus erythematosus (SLE) and analyzes factors associated with its elevation. A total of 220 patients diagnosed with SLE at the Department …
OBJECTIVES: To determine the association between hysterectomy performed for benign indications and the risk of developing BC. METHODS: A literature search was conducted in PubMed, Embase, and the Cochrane Library from database inception up…
Chronic pancreatitis (CP) is characterized by irreversible fibrotic destruction and impaired pancreatic function. CP disrupts lipid metabolism and causes the imbalance of gut microbiota which in turn exacerbates pancreatic fibrosis. Statins…
Acute pancreatitis (AP) is a leading cause of death and is commonly accompanied by systemic manifestations that are generally associated with a poor prognosis. Many cytokines contribute to pancreatic tissue damage and cause systemic injury.…
OBJECTIVE: Uterine carcinosarcomas (UCSs) are aggressive rare tumors recognized as malignancies composed of metaplastic transformation of epithelial elements. Nay no comprehensive molecular classification has been applied to UCS to guide ta…
A 14-year-old African-American girl was diagnosed with antiphospholipid-positive systemic lupus erythematosus (SLE) in July 1994. The course was complicated by nephrotic syndrome, sepsis, hemolytic anemia, acute renal failure, saphenous vei…