Lu Yang

This study aimed to assess the causal relationship between lipidome and female reproductive diseases (FRDs) using an advanced series of Mendelian randomization (MR) methods. This study utilized genome-wide association study (GWAS) summary s…

PURPOSE: Ovarian endometriosis, a prevalent condition in reproductive-age women, causes dysmenorrhea and infertility, significantly impairing quality of life. To date, there is no systematic description of ovarian endometriosis in the liter…

To explore and validate active components in the Yijing Decoction formula that exert therapeutic effects on targets associated with premature ovarian insufficiency (POI) and to identify the underlying mechanisms of action. A rat model of PO…

We report a 67-year-old female diagnosed with ovarian mesonephric-like adenocarcinoma (MLA) and treated with a comprehensive regimen. This case emphasizes the urgent need for standardized diagnostic criteria and evidence-based treatment pro…

To explore the impact of amygdalin on the proliferation, migration, and invasion of human endometrial stromal cells (HESCs) and the possible underlying mechanism. HESCs were incubated with 50, 100, and 200 µg/mL of amygdalin. The malignant …

The human vascular system, comprising endothelial cells (ECs) and mural cells, covers a vast surface area in the body, providing a critical interface between blood and tissue environments. Functional differences exist across specific vascul…

The occurrence of ovarian cancer (OC) is a major factor in women's mortality rates. Despite progress in medical treatments, like new drugs targeting homologous recombination deficiency, survival rates for OC patients are still not ideal. Th…

The post-transcriptional N6-methyladenosine (m6A) modification of RNA influences stability, transport, and translation with implications for various physiological and pathological processes. Immune cell development, differentiation, and act…

BACKGROUND: Acute myeloid leukemia (AML) patients with normal karyotype (NK-AML) have significant variabilities in outcomes. The European Leukemia Net stratification system and some prognostic models have been used to evaluate risk stratifi…

Objective: To evaluate the incidence of deeply infiltrating endometriosis (DIE) among patients of pelvic endometriosis confirmed by pathology and to make analysis of its clinical and pathological characteristics. Methods: From January 1, 20…

BACKGROUND: Estrogen is involved in the pathophysiological process of benign prostatic hyperplasia (BPH), in which epithelial-mesenchymal transition (EMT) plays an important role. Upregulation of aquaporin (AQP) 5, which is directly activat…

BACKGROUND: Traditional Chinese Medicine has considerable public support in Australia and elsewhere around the world; the literature suggests Chinese medicine (CM) and acupuncture are particularly popular. AIM: To examine factors associate…

Endometriosis is one of the major female health burdens which affects the quality of life and reproductive potential of individuals. Although some treatment strategies are available, the complete cure of endometriosis is not yet possible. I…

Background: The WNT4 gene plays an important role in female sex determination and differentiation. It also contributes to maintaining of the ovaries and the survival of follicles. Methods: We sequenced the coding region and splice sites of …