Endometriosis is the major cause of female infertility and has been linked to the action of estrogen and estrogen receptor (ER). A new pool of ERβ locates within mitochondria, which regulates the endometriotic cell withstanding external ins…
Estrogen enhances mitochondrial function by enhancing mitochondrial biogenesis and sustaining mitochondrial energy-transducing capacity. Shifts in mitochondrial bioenergetic pathways from oxidative phosphorylation to glycolysis have been hy…
OBJECTIVE: To identify the impact of the pluripotent transcription factor OCT4 in endometrial cell migration and endometriosis. DESIGN: The OCT4 expression and cell migration study. SETTING: Research institution and reproductive medical c…
Endometriosis, a frequently encountered disease in gynecology, is a considerable threat to the physical, psychological, and social integrity of women. Moreover, up to 50% of infertile patients have this disease. The etiology and pathogenesi…
OBJECTIVE: To induce apoptosis of endometriotic cells of patients with endometriosis. DESIGN: To demonstrate that polyglycolic acid/chitosan glue directly inhibits cell proliferation by inducing apoptosis. SETTING: University hospital inf…