Jiaxin Peng

ORCID: 0000-0003-2054-5342 · 2 papers in corpus

lab-animal 2026

Senescence-Driven Remodeling Defines an Aggressive and Immunomodulatory Subtype of Endometriosis

Aging cell ·doi:10.1111/acel.70463

Endometriosis is a benign yet invasive disease characterized by ectopic endometrial growth and immune remodeling. While emerging evidence implicates cellular senescence in disease progression, the underlying mechanisms remain largely undefi…

lab-animal 2025

Harmine inhibits oxidative phosphorylation, thus regulating the polarization of macrophages mediated by extracellular adenosine in endometriosis

Human Reproduction ·doi:10.1093/humrep/deaf130

STUDY QUESTION: Can harmine mitigate endometriosis by modulating oxidative phosphorylation (OXPHOS) suppression and macrophage polarization? SUMMARY ANSWER: Harmine induces apoptosis in endometriotic lesions by inhibiting OXPHOS while also…