Yan R

ORCID: 0000-0002-5779-9090 · 12 papers in corpus
lab-animal 2026
Translational research : the journal of laboratory and clinical medicine ·doi:10.1016/j.trsl.2026.06.002

BACKGROUND: Pregnant women, as well as patients with endometriosis and some ovarian tumors, may experience a state of high estrogen levels. However, the role of high estrogen in platelet function and thrombosis remains controversial, which …

review 2025
Cell death discovery ·doi:10.1038/s41420-025-02324-z

With the development of public health, female diseases have become the focus of current concern. The unique reproductive anatomy of women leads to the development of gynecological diseases gradually become an important part of the socio-eco…

other 2025
Frontiers in immunology ·doi:10.3389/fimmu.2025.1680849

BACKGROUND: Endometriosis (EM) is a chronic gynecological disorder that affects 5% to 10% of women of childbearing age, often causing pelvic pain and infertility. Fibrosis is a hallmark of EM progression, yet its underlying molecular driver…

review 2025
Frontiers in pharmacology ·doi:10.3389/fphar.2025.1534798

Formononetin (FMN) is a common natural metabolite that can be extracted and isolated from some common botanical drugs. In recent years, FMN has garnered increasing attention due to its beneficial biological activities. In this paper, we sys…

lab-animal 2025
Journal of ovarian research ·doi:10.1186/s13048-025-01683-6

Long non-coding RNAs (lncRNAs) affect the biological functions of granulosa cells (GCs) through multiple mechanisms, including epigenetic regulation, transcriptional regulation, post-translational modification, and cell signaling. Our previ…

observational 2025
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-025-01416-w

BACKGROUND: Insulin resistance(IR) is a key mechanism underlying both obesity and metabolic syndrome, with significant implications for the onset and progression of female infertility. This study systematically examines the associations bet…

review 2023
Toxics ·doi:10.3390/toxics11121000

Reproductive disorders are considered a global health problem influenced by physiological, genetic, environmental, and lifestyle factors. The increased exposure to bisphenols, a chemical used in large quantities for the production of polyca…

other 2023
Radiology and oncology ·doi:10.2478/raon-2023-0023

BACKGROUND: The aim of the study was to investigate the value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and intravoxel incoherent motion (IVIM) in differentiating TP53-mutant from wild type, low-risk from non-low-ris…

other 2022
Frontiers in oncology ·doi:10.3389/fonc.2022.876120

BACKGROUND: Endometrial cancer (EC) is one of the most common gynecologic malignancies in clinical practice. This study aimed to compare the value of diffusion-weighted imaging (DWI), diffusion kurtosis imaging (DKI), and amide proton trans…

diagnostic-accuracy 2018
Cancer imaging : the official publication of the International Cancer Imaging Society ·doi:10.1186/s40644-018-0156-6

BACKGROUND: The invasion depth of endometrial cancer is one of the most important prognosis factors. The aim of the current study was to investigate the diagnostic value of the apparent diffusion coefficient (ADC) of the peritumoral zone fo…

other 2016
Experimental and therapeutic medicine ·doi:10.3892/etm.2015.2924

The aim of the present study was to investigate the association between serum vascular endothelial growth factor (VEGF) and insulin-like growth factor 1 (IGF-1) levels and the prognosis of patients with uterine fibroids following uterine ar…

lab-animal 2013
PloS one ·doi:10.1371/journal.pone.0067846

The down-regulation of microRNA-196b (miR-196b) has been reported, but its contribution to cervical cancer progression remains to be investigated. In this study, we first demonstrated that miR-196b down-regulation was significantly associat…