Andreas Kaiser

ORCID: 0000-0002-7758-6500 · 3 papers in corpus
rct 2023
Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study
European journal of endocrinology ·doi:10.1093/ejendo/lvad063

OBJECTIVE: Aldo-keto reductase 1C3 (AKR1C3) has been postulated to be involved in androgen, progesterone, and estrogen metabolism. Aldo-keto reductase 1C3 inhibition has been proposed for treatment of endometriosis and polycystic ovary synd…

rct 2020
Effect of Food Intake on the Pharmacokinetics of the Selective Progesterone Receptor Modulator Vilaprisan: A Randomized Clinical Study in Healthy Postmenopausal Women
Clinical pharmacology in drug development ·doi:10.1002/cpdd.876

This exploratory, open-label, randomized, 3-period crossover study in 12 healthy postmenopausal women investigated the effects of food intake on the pharmacokinetics of vilaprisan. Single doses of vilaprisan (2 mg) were administered under f…

observational 2007
Untersuchungen zur klinischen Bedeutung Endometriose-assoziierter Nervenfasern (EM-aNF) in peritonealen Endometrioseläsionen (pEM)
·doi:10.1055/s-2007-989158

Fragestellung: Endometriose ist typischerweise mit chronisch rezidivierenden Unterbauchschmerzen assoziiert, wobei die Pathogenese der Schmerzentstehung weitest gehend ungeklärt ist. In pEM von symptomatischen Patientinnen konnten in 74,5% …