OBJECTIVES: To determine whether anogenital distance (AGD), a potential non-invasive biomarker reflecting prenatal androgen exposure, differs between adolescents with laparoscopically confirmed endometriosis and matched controls. METHODS: …
STUDY OBJECTIVE: To evaluate the efficacy and tolerability of the gonadotropin-releasing hormone antagonist elagolix for endometriosis-associated pain symptoms in adolescents and young adults (AYAs) METHODS: We performed a retrospective coh…
BACKGROUND: Testosterone therapy can also lead to physiologic changes in structures such as the endometrium and ovaries. Given this, testosterone may alter uterine bleeding patterns. Although ultrasounds are routinely performed for the purp…
OBJECTIVE: To compare the postoperative diagnoses and the types of surgical intervention, excluding hysterectomy, between adolescents and adults receiving endometriosis surgery. DESIGN: Retrospective cohort study. SUBJECTS: Adolescents (a…
(Abstracted from J Pediatr Adolesc Gynecol 2024;37(4):402–406 One of the leading causes of dysmenorrhea in adolescents is endometriosis, or the growth of endometrial tissue outside the uterus. Endometriosis significantly impacts quality of …
BACKGROUND: Danazol is a synthetic progestin with androgenic effects that is approved by the Food and Drug Administration for treatment of endometriosis, benign fibrocystic breast disease, and hereditary angioedema. In recent years, increas…
STUDY OBJECTIVE: To evaluate the efficacy and tolerability of a progestin-only pill containing 4 mg drospirenone (DRSP) as a hormonal therapy for the management of endometriosis-associated symptoms in adolescents and young adults. DESIGN: …