Wei Yan
ORCID: 0000-0002-6972-7393
· 14 papers in corpus
other
2026
OBJECTIVE: To address the urgent need for non-invasive diagnosis of endometriosis, this study developed a novel microfluidic platform utilizing a three-dimensional (3D) polydimethylsiloxane scaffold microchip to efficiently capture circula…
other
2026
Evolutionary mismatches between the reproductive life histories of women in industrialized societies and their Paleolithic ancestors are established risk factors for gynecological pathologies and breast cancer. In contemporary women, these …
review
2026
BACKGROUND: Ovarian cancer remains one of the deadliest gynecologic malignancies. Poor outcomes largely reflect late diagnosis, marked inter- and intratumoral heterogeneity, and variable treatment response. METHODS: This review summarizes …
other
2026
BACKGROUND: Endometriosis is a chronic inflammatory disorder that significantly compromises women's health, typically manifesting as pelvic pain and/or infertility. This condition imposes a substantial burden on global healthcare systems. …
2026
BackgroundEndometriosis is a chronic inflammatory disorder that significantly compromises women's health, typically manifesting as pelvic pain and/or infertility. This condition imposes a substantial burden on global healthcare systems.Meth…
2026
Fei Liu,1,2,* Suzhen Yuan,1,2,* Qing Yan,1,2 Shuhao Yang,1,2 Wei Yan,1,2 Tao Xiang,1,2 Zhangying Wu,3 Guirong Li,3 Wu Ren,1,2 Wenwen Wang1,2 1Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics …
lab-animal
2025
As an emerging endocrine-disrupting agent and structural analog of bisphenol A (BPA), bisphenol B (BPB) raises significant concerns due to its potential to induce male reproductive toxicity. Despite its presence in maternal bodily fluids, t…
other
2024
lab-animal
2021
As a common gynecologic disease, endometriosis (EM) poses a threat to the reproductive health of about 10% women globally. Recent studies have revealed that circular RNAs (circRNAs) are deeply implicated in EM pathogenesis. However, the fun…
other
2021
The high rate of SARS-CoV-2 infection poses a serious threat to public health. Previous studies have suggested that SARS-CoV-2 can infect human ovary, the core organ of the female reproductive system. However, it remains unclear which type …
lab-animal
2020
Gonadotrophin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone, is the main regulator of the reproductive system, acting on gonadotropic cells by binding to the GnRH1 receptor (GnRH1R). The GnRH-GnRH1R system is…
other
2018
This study aimed to study the expression of homeobox (HOX)A11-AS1 ( HOXA11 antisense RNA) long noncoding RNA (lncRNA) and the expression of homeobox A ( HOXA9, HOXA10, HOXA11, and HOXA13) genes in the eutopic (EU) and ectopic (EC) endometri…
lab-animal
2018
BACKGROUND AND OBJECTIVE: Mammalian sterile 20-like kinase 1 (Mst1) plays a critical role in regulating cell survival and apoptosis. However, its influence on gastric cancer cell viability is not understood. Our study aims to explore the sp…
other
2017
Circular RNAs (circRNAs) are a unique class of endogenous RNAs which could be used as potential diagnostic and prognostic biomarkers of many diseases. Our study aimed to investigate circRNA profiles in human granulosa cells (GCs) during mat…