Xiaoyue Sun

ORCID: 0000-0001-8167-3108 · 3 papers in corpus
lab-animal 2026
Dose-Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload
Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202521702

Iron overload induces cellular stress and is implicated in diverse pathological conditions. Nevertheless, the epigenetic mechanisms governing mammalian cellular responses to iron overload remain poorly characterized. Using multi-omics profi…

other 2024
Comparison of chromatin accessibility remodeling of granulosa cells in patients with endometrioma or pelvic/tubal infertility
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-024-03302-7

PURPOSE: To elucidatethe epigenetic alteration associated with impaired oogenesis in endometrioma using multi-omic approaches. METHODS: ATAC-seq was performed on the granulosa cells (GCs) of 6 patients (3 with endometrioma and 3 without). …

review 2022
Understanding recurrent pregnancy loss: recent advances on its etiology, clinical diagnosis, and management
Medical review (2021) ·doi:10.1515/mr-2022-0030

Recurrent pregnancy loss (RPL) has become an important reproductive health issue worldwide. RPL affects about 2%-3% of reproductive-aged women, and makes serious threats to women's physical and mental health. However, the etiology of approx…