Paul Webster

The pathogenic mechanisms underlying acute pancreatitis are not clear. Two key pathologic acinar cell responses of this disease are vacuole accumulation and trypsinogen activation. We show here that both result from defective autophagy, by …

Condoms vasectomies and coitus interruptus are widely used by men but all have serious drawbacks. Vasectomies are generally irreversible; and condoms and withdrawal are said to reduce male sexual pleasure. Danazol has shown promise as a mal…