Zhen-Shan Yang

No ORCID on file · 2 papers in corpus

lab-animal 2025

Participation of COX2/mPGES1/PGE2 in mouse and human endometrial stromal decidualization

BMC veterinary research ·doi:10.1186/s12917-025-04505-5

BACKGROUND: Prostaglandin E2 (PGE2) is vital for embryo implantation and decidualization. Whether COX2/mPGES1/PGE2 pathway is essential for mouse and human decidualization remains unclear. RESULTS: This study showed that mPGES1 was highly …

lab-animal 2023

METTL3 is essential for normal progesterone signaling during embryo implantation via m6A-mediated translation control of progesterone receptor

Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2214684120

Embryo implantation, a crucial step in human reproduction, is tightly controlled by estrogen and progesterone (P4) via estrogen receptor alpha and progesterone receptor (PGR), respectively. Here, we report that N6-methyladenosine (m6A), the…